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CAZyme Information: MGYG000001338_00955

You are here: Home > Sequence: MGYG000001338_00955

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Blautia_A wexlerae_A
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A wexlerae_A
CAZyme ID MGYG000001338_00955
CAZy Family GH36
CAZyme Description Alpha-galactosidase AgaA
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
740 MGYG000001338_1|CGC15 85385.12 5.4645
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001338 3930699 Isolate not provided not provided
Gene Location Start: 1067840;  End: 1070062  Strand: -

Full Sequence      Download help

MSIIFHESSK  TFHLYNNNIS  YIMTVLSNGH  LGNLYFGKRI  HDREDFSYLL  EMKQRPMTAC60
VYEGNRKFSL  EHLKLEYPVY  GSSDYRYPAV  EILQENGSRI  SDFTYVSYTI  AAGKPKLQGL120
PATYTEKDEE  AQTLCVKLKD  EVTGMVLELL  YTIFTQRGII  TRSARFTNEG  TSSVHLLNAM180
SLSLDLPDKD  YVWMQFSGAW  SRERHVKERR  LEQGIQSVGS  IRGNSSHEHN  PFIVLRRPSA240
TENAGEVMGF  SLIYSGNHRM  QAEVDTHDTT  RITVGINPQN  FDWKLDCGES  FQTPEAVVVF300
SDKGLNGMSQ  TFHKLYQKRL  ARGYWRDRPR  PILNNNWEAT  YFDFTEDRLV  EIAAKAKECG360
VELFVLDDGW  FGARSNDYAG  LGDWVANRER  LPQGIKGIAD  RIEEMGMKFG  LWFEPEMVNK420
DSDLYRAHPD  WILQTPQRHS  CHGRNQYVLD  FSRKEVVDCI  YEMMYKILSE  AKVSYIKWDM480
NRSITECYSA  ALPADRQGEV  FHRYILGVYD  LYERLNTAFP  QILFESCASG  GGRFDPGILY540
YAPQGWTSDD  TDAAERVKIQ  YGTSMCYPVS  SMGSHVSVVP  NHQLNRKTPL  HTRANVAYFG600
TFGYELDLNK  LSDEEISEVK  QQITFMKEYR  ELIQFGTFYR  LKSPFEGNET  VWMTVSEDKK660
TALVFWYRER  NVVNADFTRV  RLQGLDPDLI  YRNEYNETEN  YGDELMNLGL  LTTDCTAGEP720
TSEDEPCTDY  ESRIYVLTAK  740

Enzyme Prediction      help

EC 3.2.1.22

CAZyme Signature Domains help

Created with Snap377411114818522225929633337040744448151855559262966670312710GH36
Family Start End Evalue family coverage
GH36 12 710 3.7e-296 0.9941860465116279

CDD Domains      download full data without filtering help

Created with Snap377411114818522225929633337040744448151855559262966670312710GalA290636Melibiase329628GH3629286Glyco_hydro_36N649737Glyco_hydro_36C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3345 GalA 0.0 12 710 4 665
Alpha-galactosidase [Carbohydrate transport and metabolism].
pfam02065 Melibiase 0.0 290 636 1 347
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd14791 GH36 8.48e-152 329 628 1 299
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam16875 Glyco_hydro_36N 3.66e-124 29 286 1 256
Glycosyl hydrolase family 36 N-terminal domain. This domain is found at the N-terminus of many family 36 glycoside hydrolases. It has a beta-supersandwich fold.
pfam16874 Glyco_hydro_36C 5.72e-26 649 737 1 78
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.

CAZyme Hits      help

Created with Snap37741111481852222592963333704074444815185555926296667033740CBL25056.1|GH363740QRT48597.1|GH361740CBK83747.1|GH361739QIB59452.1|GH361740SNU95754.1|GH36
Hit ID E-Value Query Start Query End Hit Start Hit End
CBL25056.1 0.0 3 740 4 741
QRT48597.1 0.0 3 740 4 741
CBK83747.1 0.0 1 740 1 774
QIB59452.1 0.0 1 739 1 740
SNU95754.1 0.0 1 740 1 741

PDB Hits      download full data without filtering help

Created with Snap377411114818522225929633337040744448151855559262966670317104FNQ_A17104FNR_A17104FNU_A17104FNT_A17104FNP_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNQ_A 2.26e-272 1 710 1 708
Crystalstructure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNR_A 1.48e-270 1 710 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_B Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_C Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNR_D Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus [Geobacillus stearothermophilus]
4FNU_A 1.38e-268 1 710 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus],4FNU_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose [Geobacillus stearothermophilus]
4FNT_A 1.96e-268 1 710 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_B Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_C Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus],4FNT_D Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose [Geobacillus stearothermophilus]
4FNP_A 2.77e-268 1 710 1 708
Crystalstructure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNP_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus [Geobacillus stearothermophilus],4FNS_A Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_B Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_C Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus],4FNS_D Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin [Geobacillus stearothermophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap37741111481852222592963333704074444815185555926296667031710sp|Q9ALJ4|AGAA_GEOSE3710sp|G1UB44|MELA_LACAC7710sp|P43467|AGAL1_PEDPE1710sp|G4T4R7|AGASK_RUMGN71710sp|Q0CEF5|AGALG_ASPTN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9ALJ4 8.12e-270 1 710 1 708
Alpha-galactosidase AgaA OS=Geobacillus stearothermophilus OX=1422 GN=agaA PE=1 SV=1
G1UB44 8.01e-235 3 710 6 712
Alpha-galactosidase Mel36A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=melA PE=1 SV=1
P43467 1.19e-226 7 710 8 711
Alpha-galactosidase 1 OS=Pediococcus pentosaceus OX=1255 GN=agaR PE=3 SV=1
G4T4R7 9.58e-202 1 710 1 701
Bifunctional alpha-galactosidase/sucrose kinase AgaSK OS=Ruminococcus gnavus OX=33038 GN=agaSK PE=1 SV=1
Q0CEF5 7.89e-181 71 710 67 707
Probable alpha-galactosidase G OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=aglG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000036 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001338_00955.