dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000001345_03315

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Basic Information help

Species

Bacteroides xylanisolvens

Lineage

Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides xylanisolvens

CAZyme ID

MGYG000001345_03315

CAZy Family

GH154

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
853	MGYG000001345_35\|CGC10	96179.73	7.7377

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001345	5913018	Isolate	not provided	not provided

Gene Location

Start: 839213; End: 841774 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000001345_03315.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH154	474	832	4.7e-105	0.9942528735632183

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd16026	GALNS_like	0.0	22	438	1	398	galactosamine-6-sulfatase; also known as N-acetylgalactosamine-6-sulfatase (GALNS). Lysosomal galactosamine-6-sulfatase removes sulfate groups from a terminal N-acetylgalactosamine-6-sulfate (or galactose-6-sulfate) in mucopolysaccharides such as keratan sulfate and chondroitin-6-sulfate. Defects in GALNS lead to accumulation of substrates, resulting in the development of the lysosomal storage disease mucopolysaccharidosis IV A.
pfam10022	DUF2264	6.21e-141	474	834	1	351	Uncharacterized protein conserved in bacteria (DUF2264). Members of this family of hypothetical bacterial proteins have no known function.
cd16144	ARS_like	1.37e-119	23	456	1	421	uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.
cd16146	ARS_like	1.45e-116	23	456	1	404	uncharacterized arylsulfatase. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.
cd16142	ARS_like	1.07e-115	23	438	1	371	uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QDH57428.1	0.0	1	853	1	853
QUT45002.1	2.67e-253	468	853	26	411
QRQ50327.1	2.48e-252	468	853	11	396
QDO70981.1	2.06e-237	473	853	30	410
QRQ48195.1	9.21e-218	474	852	30	408

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1E1Z_P	6.96e-66	23	438	3	423	Crystalstructure of an Arylsulfatase A mutant C69S [Homo sapiens]
1E3C_P	6.96e-66	23	438	3	423	Crystalstructure of an Arylsulfatase A mutant C69S soaked in synthetic substrate [Homo sapiens]
1E2S_P	1.83e-65	23	438	3	423	Crystalstructure of an Arylsulfatase A mutant C69A [Homo sapiens]
1AUK_A	3.49e-65	23	438	3	423	HumanArylsulfatase A [Homo sapiens],1N2K_A Crystal structure of a covalent intermediate of endogenous human arylsulfatase A [Homo sapiens],1N2L_A Crystal structure of a covalent intermediate of endogenous human arylsulfatase A [Homo sapiens]
1E33_P	2.42e-64	23	438	3	423	Crystalstructure of an Arylsulfatase A mutant P426L [Homo sapiens]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q32KJ9	8.30e-71	6	455	18	481	Arylsulfatase G OS=Rattus norvegicus OX=10116 GN=Arsg PE=2 SV=1
Q32KH9	9.35e-68	7	435	19	465	Arylsulfatase G OS=Canis lupus familiaris OX=9615 GN=ARSG PE=2 SV=1
Q3TYD4	1.02e-67	8	452	20	482	Arylsulfatase G OS=Mus musculus OX=10090 GN=Arsg PE=1 SV=1
P50428	3.14e-66	10	438	8	440	Arylsulfatase A OS=Mus musculus OX=10090 GN=Arsa PE=1 SV=2
P15289	8.48e-66	10	438	9	441	Arylsulfatase A OS=Homo sapiens OX=9606 GN=ARSA PE=1 SV=3

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000317	0.999024	0.000184	0.000158	0.000141	0.000136

TMHMM Annotations help

There is no transmembrane helices in MGYG000001345_03315.