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CAZyme Information: MGYG000001345_04027
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides xylanisolvens | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides xylanisolvens | |||||||||||
| CAZyme ID | MGYG000001345_04027 | |||||||||||
| CAZy Family | GT6 | |||||||||||
| CAZyme Description | O-antigen biosynthesis glycosyltransferase WbnI | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 658626; End: 659417 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT6 | 2 | 220 | 2.1e-75 | 0.7714285714285715 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd02515 | Glyco_transf_6 | 3.58e-47 | 2 | 214 | 35 | 245 | Glycosyltransferase family 6 comprises enzymes responsible for the production of the human ABO blood group antigens. Glycosyltransferase family 6, GT_6, comprises enzymes with three known activities: alpha-1,3-galactosyltransferase, alpha-1,3 N-acetylgalactosaminyltransferase, and alpha-galactosyltransferase. UDP-galactose:beta-galactosyl alpha-1,3-galactosyltransferase (alpha3GT) catalyzes the transfer of galactose from UDP-alpha-d-galactose into an alpha-1,3 linkage with beta-galactosyl groups in glycoconjugates. The enzyme exists in most mammalian species but is absent from humans, apes, and old world monkeys as a result of the mutational inactivation of the gene. The alpha-1,3 N-acetylgalactosaminyltransferase and alpha-galactosyltransferase are responsible for the production of the human ABO blood group antigens. A N-acetylgalactosaminyltransferases use a UDP-GalNAc donor to convert the H-antigen acceptor to the A antigen, whereas a galactosyltransferase uses a UDP-galactose donor to convert the H-antigen acceptor to the B antigen. Alpha-1,3 N-acetylgalactosaminyltransferase and alpha-galactosyltransferase differ only in the identity of four critical amino acid residues. |
| pfam03414 | Glyco_transf_6 | 5.12e-43 | 3 | 216 | 53 | 264 | Glycosyltransferase family 6. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QDH53874.1 | 9.95e-205 | 1 | 263 | 1 | 263 |
| QRM99205.1 | 9.95e-205 | 1 | 263 | 1 | 263 |
| QUT26666.1 | 8.88e-198 | 1 | 254 | 1 | 254 |
| QUT78828.1 | 3.99e-186 | 1 | 263 | 1 | 263 |
| ALJ48119.1 | 3.99e-186 | 1 | 263 | 1 | 263 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4AYJ_A | 1.82e-177 | 1 | 246 | 1 | 246 | Molecularstructure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYJ_B Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYJ_C Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYJ_D Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYL_A Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus] |
| 4CJB_A | 5.21e-177 | 1 | 246 | 1 | 246 | orthorhombiccrystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJB_B orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJB_C orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJB_D orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJC_A orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus],4CJC_B orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus],4CJC_C orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus],4CJC_D orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus] |
| 4CJ8_A | 5.60e-177 | 1 | 246 | 3 | 248 | monocliniccrystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_B monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_C monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_D monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_E monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_F monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_G monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_H monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_I monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_J monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_K monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_L monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_M monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_N monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_O monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_P monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus] |
| 1R7T_A | 1.39e-31 | 3 | 218 | 54 | 270 | GlycosyltransferaseA in complex with 3-deoxy-acceptor analog inhibitor [Homo sapiens],1R7V_A Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor [Homo sapiens],1R7Y_A Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate [Homo sapiens],1R81_A Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate-N-acetyl-galactose [Homo sapiens] |
| 1LZ0_A | 1.68e-31 | 3 | 218 | 54 | 270 | GlycosyltransferaseA [Homo sapiens],1LZI_A Glycosyltransferase A + UDP + H antigen acceptor [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q5ZLK4 | 5.01e-37 | 1 | 235 | 105 | 340 | Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 OS=Gallus gallus OX=9031 GN=GBGT1 PE=2 SV=1 |
| Q5JBG6 | 4.96e-35 | 1 | 239 | 1 | 231 | O-antigen biosynthesis glycosyltransferase WbnI OS=Escherichia coli OX=562 GN=wbnI PE=1 SV=1 |
| P38649 | 1.80e-33 | 3 | 218 | 95 | 311 | Histo-blood group ABO system transferase OS=Mus musculus OX=10090 GN=Abo PE=1 SV=2 |
| Q9ET32 | 4.78e-33 | 3 | 218 | 111 | 327 | Histo-blood group ABO system transferase 1 OS=Rattus norvegicus OX=10116 GN=Abo PE=1 SV=1 |
| Q95158 | 2.57e-31 | 1 | 214 | 109 | 320 | Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 OS=Canis lupus familiaris OX=9615 GN=GBGT1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000032 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |