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CAZyme Information: MGYG000001345_04584
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides xylanisolvens | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides xylanisolvens | |||||||||||
| CAZyme ID | MGYG000001345_04584 | |||||||||||
| CAZy Family | GH89 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1471291; End: 1473447 Strand: + | |||||||||||
Full Sequence Download help
| MIHTIIKYLL ISTTLFFCSC HKPKTDIITP AKQLIERQIG ERAQSIHFEY IEPSEGKDIF | 60 |
| EVIASDGRLT LRGSSSVAIC YAFHTYMKEA CKSMKTWSGE HITSVMPWPD YELYEQMSPY | 120 |
| ELRYFLNVCT FGYTTPYWDW ERWEKEIDRM ALYGVNMPLA TVASEAIAER VWLRMGLNKE | 180 |
| EIREFFTAPA HLPWHRMGNL NKWDGPLSDT WQQNQIALQH QILTRMRELG MQPIAPAFAG | 240 |
| FVPEAFAQKH PDTQFRHMRW GGFDEEYNAY VLPPDSPFFE EIGKLFVEEW EKEFGENTYY | 300 |
| LSDSFNEMEL PIDKEDKEAK YKLLTEYGET IYKSITAGNP DAVWVTQGWT FGYQHSFWDK | 360 |
| ESLKALLSNV PDDKMIIIDL GNDYPKWVWN TEQTWKVHDG FYGKKWIFSY VPNFGGKNTM | 420 |
| TGDLDMYASS SVKALRAANK GNLIGFGSAP EGLENNEVVY ELLADMGWSS DSIDLDDWMK | 480 |
| IYCEARYGGY PDAMEEAWKL FRKTAYSSLY SYPRFTWQTV VPDQRRISKI DLSDDYLQAI | 540 |
| RLYASCADEL KSSELYRNDL IEFVSYYLAA KAENFYKQAL KDDSENRVFA AQRNLQQTVD | 600 |
| LLMDVDRLLA SHPLYRLEEW VEFARNSGTT LQEKDAYEAN AKRLITSWGG IQEDYAARFW | 660 |
| SGLIKDYYIP RIQLYFTKDR NKIREWEEQW ITSPWSNSTT PFDDPVKAAL NLIEKTNK | 718 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH89 | 66 | 714 | 2.9e-212 | 0.995475113122172 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam05089 | NAGLU | 6.88e-173 | 123 | 470 | 1 | 333 | Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. |
| pfam12972 | NAGLU_C | 6.50e-48 | 478 | 709 | 1 | 257 | Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. |
| pfam12971 | NAGLU_N | 2.04e-25 | 29 | 109 | 1 | 81 | Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This N-terminal domain has an alpha-beta fold. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUR45704.1 | 0.0 | 1 | 718 | 1 | 718 |
| QUT26062.1 | 0.0 | 1 | 718 | 1 | 718 |
| QDH53248.1 | 0.0 | 1 | 718 | 1 | 718 |
| ALJ47490.1 | 0.0 | 1 | 718 | 1 | 718 |
| QRQ58948.1 | 0.0 | 1 | 718 | 1 | 718 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4XWH_A | 1.03e-118 | 68 | 675 | 51 | 655 | Crystalstructure of the human N-acetyl-alpha-glucosaminidase [Homo sapiens] |
| 2VC9_A | 1.74e-82 | 32 | 671 | 175 | 816 | Family89 Glycoside Hydrolase from Clostridium perfringens in complex with 2-acetamido-1,2-dideoxynojirmycin [Clostridium perfringens],2VCA_A Family 89 glycoside hydrolase from Clostridium perfringens in complex with beta-N-acetyl-D-glucosamine [Clostridium perfringens],2VCB_A Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with PUGNAc [Clostridium perfringens],2VCC_A Family 89 Glycoside Hydrolase from Clostridium perfringens [Clostridium perfringens] |
| 7MFK_A | 1.97e-82 | 32 | 671 | 183 | 824 | ChainA, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124],7MFL_A Chain A, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124] |
| 4A4A_A | 1.73e-81 | 32 | 671 | 198 | 839 | CpGH89(E483Q, E601Q), from Clostridium perfringens, in complex with its substrate GlcNAc-alpha-1,4-galactose [Clostridium perfringens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9FNA3 | 3.85e-121 | 31 | 708 | 49 | 789 | Alpha-N-acetylglucosaminidase OS=Arabidopsis thaliana OX=3702 GN=NAGLU PE=2 SV=1 |
| P54802 | 1.45e-117 | 68 | 675 | 74 | 678 | Alpha-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=NAGLU PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000000 | 0.000004 | 1.000018 | 0.000000 | 0.000000 | 0.000000 |