CAZyme Information: MGYG000001372_01492

Basic Information

• Species: Paraprevotella xylaniphila
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; Paraprevotella xylaniphila
• CAZyme ID: MGYG000001372_01492
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
863		99410.32	6.2928

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001372	3789432	Isolate	not provided	not provided

• Gene Location: Start: 103824; End: 106415 Strand: -

Full Sequence      

MRKRRMLMVLLAVSWLIGSAWAIDNKGITFGQPAADCFTLVEGGEVTPILLDEKDDIGVA
IAAKNLQDDFRKVTGMQAELLHSVKGKRLIVVGSLESRFVKELVKTKKIDITSLEGKREK
YLMRAVSRPFDGVDEAWVVIGSDKRGTIYGIYELSEQIGVSPWYDWADVPVVQRKNLYIQ
RGEYTAGEPAVRYRGIFLNDEAPCLTGWVKHTYGTNYGDHRFYARVFELILRLRGNFMWP
AMWSWNFYADDPENSRTARDMGIIMGTSHHEPMARNHQEWARKRRQYGVWDYATNQKVLD
RFFREGIERAKDTEDLITIGMRGDGDAPMGGKEGADHEYVNRDEYNMNLLEKVIKNQRKI
IRDVTGRPADERPQVWAIYKEVQRFYDMGLRVPDDVIMLLCDDNWGNVRRLPNAEERKRP
GGWGMYYHVDYVGAPRNSKWLNVTPIQNMWEQLQLTYDYGVDKLWILNVGDLKPMEYPIT
LFLDMAWNPKRYTADNLLEHPRGFCARQFGEEQADEAARILNLYSKYNGRVTPEMLDCHT
YNIETGEWKQVADEYRKLEADALRQYLSLPQEYHDAYKQLILFPVQAMANLYEMYYAQAM
NHKLYEENNPQANVWADKVAQAFKFDSLLCDDYNNVMSGGKWKNMMVQKHIGYTSWNDNF
RADIMPKVFRIENPEQQKGGYVFTGKYGVVSMEAEHYFEAKPAATADWTAIPYLGRTLSG
VALMPYTEGVEGASLTYKMAIPENVSEVNVHVVVKSTLAFHDVKGHEYSVGFEGGKETVV
NFNANLNEEPENVYNVFYPTVARRVVEKVVKLAVPPSADGMQLLILKPLDPGIVFEKIVV
DCGGYQKSYLFMDESPCKRDLRK

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	36	838	1.6e-279	0.9971305595408895

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	187	535	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	2.45e-34	682	854	1	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	9.86e-05	59	154	33	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADD61499.1	0.0	1	860	1	859
EEC54467.1	0.0	10	860	9	859
QRQ48278.1	0.0	10	860	9	859
QUT46101.1	0.0	10	860	9	859
ABR37760.1	0.0	22	860	21	859

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	33	862	39	856	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	0.0	24	859	3	838	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	0.0	24	859	2	837	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	1.63e-176	40	685	16	648	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	3.55e-121	58	674	31	664	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000289	0.999033	0.000182	0.000176	0.000157	0.000146

TMHMM  Annotations     

start	end
7	24