dbCAN-seq: a database of CAZyme sequence and annotation

You are browsing environment: HUMAN GUT

help

CAZyme Information: MGYG000001375_00577

You are here: Home > Sequence: MGYG000001375_00577

Basic Information help

Species

Ruminococcus_F champanellensis

Lineage

Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_F; Ruminococcus_F champanellensis

CAZyme ID

MGYG000001375_00577

CAZy Family

GH44

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
757	MGYG000001375_1\|CGC7	81929.37	4.1168

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001375	2513436	Isolate	not provided	not provided

Gene Location

Start: 643341; End: 645614 Strand: +

Full Sequence Download help

Enzyme Prediction help

EC	3.2.1.4	3.2.1.151

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH44	32	526	2.6e-177	0.9922178988326849
CBM76	529	683	2.9e-86	0.9937888198757764

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam12891	Glyco_hydro_44	2.35e-69	88	315	1	234	Glycoside hydrolase family 44. This is a family of bacterial glycoside hydrolases formerly known as cellulase family J, and now known as Cel44A. It is one of the major enzymatic components of the cellulosome of Clostridium thermocellum strain F1 and of many other Firmicutes.
cd14256	Dockerin_I	2.89e-14	691	751	1	57	Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam00404	Dockerin_1	7.49e-10	692	750	1	55	Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.
cd14253	Dockerin	4.75e-06	692	751	1	56	Dockerin repeat domain. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.
cd14254	Dockerin_II	4.92e-04	692	750	1	53	Type II dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II dockerins, which are responsible for mediating attachment of the cellulosome complex to the bacterial cell wall.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBL16808.1	0.0	1	757	1	757
CDD54427.1	0.0	1	757	1	757
CAC83072.1	5.91e-308	32	713	36	755
AAA95959.1	2.97e-271	32	593	36	596
ERJ96918.1	1.21e-190	31	681	44	707

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2E0P_A	3.74e-150	34	525	10	514	ChainA, Endoglucanase [Acetivibrio thermocellus],2E4T_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EO7_A Chain A, Endoglucanase [Acetivibrio thermocellus]
2EEX_A	1.05e-149	34	525	10	514	ChainA, Endoglucanase [Acetivibrio thermocellus],2EJ1_A Chain A, Endoglucanase [Acetivibrio thermocellus],2EQD_A Chain A, Endoglucanase [Acetivibrio thermocellus]
3IK2_A	8.07e-136	33	527	2	511	CrystalStructure of a Glycoside Hydrolase Family 44 Endoglucanase produced by Clostridium acetobutylium ATCC 824 [Clostridium acetobutylicum ATCC 824]
2YIH_A	1.14e-127	30	526	6	516	Structureof a Paenibacillus polymyxa Xyloglucanase from GH family 44 with Xyloglucan [Paenibacillus polymyxa],2YJQ_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],2YJQ_B Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa]
2YKK_A	3.85e-125	30	526	6	516	Structureof a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa],3ZQ9_A Structure of a Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 [Paenibacillus polymyxa]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P29719	2.77e-121	2	531	5	547	Endoglucanase A OS=Paenibacillus lautus OX=1401 GN=celA PE=3 SV=1
P22533	6.67e-113	34	528	788	1305	Beta-mannanase/endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=manA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.001477	0.997167	0.000534	0.000276	0.000262	0.000245

TMHMM Annotations download full data without filtering help

start	end
7	26