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CAZyme Information: MGYG000001376_00586
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Dysgonomonas gadei | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae; Dysgonomonas; Dysgonomonas gadei | |||||||||||
| CAZyme ID | MGYG000001376_00586 | |||||||||||
| CAZy Family | GT11 | |||||||||||
| CAZyme Description | O-antigen biosynthesis glycosyltransferase WbnK | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 777613; End: 778506 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT11 | 10 | 292 | 1.1e-65 | 0.9637681159420289 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11301 | Fut1_Fut2_like | 3.97e-58 | 3 | 280 | 1 | 257 | Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
| pfam01531 | Glyco_transf_11 | 5.27e-30 | 11 | 278 | 39 | 278 | Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AMQ00833.1 | 1.71e-58 | 3 | 294 | 2 | 284 |
| ACU02372.1 | 4.54e-58 | 3 | 278 | 2 | 264 |
| ATP58492.1 | 1.28e-57 | 3 | 278 | 2 | 264 |
| QTL97698.1 | 6.56e-56 | 3 | 296 | 2 | 275 |
| ANU63125.1 | 1.09e-54 | 3 | 294 | 2 | 286 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q58YV9 | 2.68e-37 | 11 | 294 | 7 | 301 | O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1 |
| Q10980 | 2.59e-11 | 123 | 264 | 166 | 318 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Fut1 PE=2 SV=2 |
| Q9TUD6 | 1.10e-10 | 123 | 264 | 166 | 318 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Pan troglodytes OX=9598 GN=FUT1 PE=3 SV=1 |
| Q9TUD4 | 1.10e-10 | 123 | 264 | 166 | 318 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Gorilla gorilla gorilla OX=9595 GN=FUT1 PE=3 SV=1 |
| P19526 | 1.10e-10 | 123 | 264 | 165 | 317 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Homo sapiens OX=9606 GN=FUT1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000063 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |