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CAZyme Information: MGYG000001376_02365
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Dysgonomonas gadei | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae; Dysgonomonas; Dysgonomonas gadei | |||||||||||
| CAZyme ID | MGYG000001376_02365 | |||||||||||
| CAZy Family | GH42 | |||||||||||
| CAZyme Description | Beta-galactosidase BgaA | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 386693; End: 388765 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH42 | 37 | 411 | 9.1e-122 | 0.9919137466307277 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam02449 | Glyco_hydro_42 | 4.18e-149 | 36 | 413 | 1 | 376 | Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues. |
| COG1874 | GanA | 2.18e-101 | 37 | 690 | 22 | 672 | Beta-galactosidase GanA [Carbohydrate transport and metabolism]. |
| pfam08532 | Glyco_hydro_42M | 1.96e-56 | 430 | 631 | 1 | 198 | Beta-galactosidase trimerisation domain. This is non catalytic domain B of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. This domain is related to glutamine amidotransferase enzymes, but the catalytic residues are replaced by non functional amino acids. This domain is involved in trimerisation. |
| cd03143 | A4_beta-galactosidase_middle_domain | 3.28e-20 | 432 | 635 | 1 | 154 | A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. This group includes proteins similar to beta-galactosidase from Thermus thermophilus. Beta-Galactosidase hydrolyzes the beta-1,4-D-galactosidic linkage of lactose, as well as those of related chromogens, o-nitrophenyl-beta-D-galactopyranoside (ONP-Gal) and 5-bromo-4-chloro-3-indolyl-beta-D-galactoside (X-gal). This A4 beta-galactosidase middle domain lacks the catalytic triad of typical GATase1 domains. The reactive Cys residue found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow in typical GATase1 domains is not conserved in this group. |
| pfam00150 | Cellulase | 8.47e-07 | 34 | 312 | 16 | 270 | Cellulase (glycosyl hydrolase family 5). |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QIK60332.1 | 0.0 | 6 | 690 | 5 | 692 |
| QIK54901.1 | 0.0 | 6 | 690 | 5 | 692 |
| QQA10749.1 | 0.0 | 19 | 688 | 315 | 984 |
| QUT42010.1 | 0.0 | 19 | 688 | 315 | 984 |
| BCA48690.1 | 0.0 | 19 | 688 | 322 | 991 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6LVW_A | 5.08e-106 | 33 | 666 | 3 | 645 | PolyextremophilicBeta-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi [Halorubrum lacusprofundi ATCC 49239] |
| 1KWG_A | 2.33e-96 | 32 | 690 | 1 | 644 | Crystalstructure of Thermus thermophilus A4 beta-galactosidase [Thermus thermophilus],1KWK_A Crystal structure of Thermus thermophilus A4 beta-galactosidase in complex with galactose [Thermus thermophilus] |
| 6Y2K_A | 1.52e-93 | 33 | 690 | 3 | 655 | ChainA, beta-galactosidase [Marinomonas sp. ef1] |
| 4UCF_A | 1.15e-78 | 34 | 648 | 23 | 647 | Crystalstructure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UCF_B Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UCF_C Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UZS_A Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17],4UZS_B Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17],4UZS_C Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17] |
| 4OIF_A | 1.08e-72 | 32 | 659 | 16 | 635 | 3Dstructure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus],4OIF_B 3D structure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus],4OIF_C 3D structure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P94804 | 2.34e-117 | 33 | 687 | 3 | 650 | Beta-galactosidase BgaH OS=Haloferax lucentense (strain DSM 14919 / JCM 9276 / NCIMB 13854 / Aa 2.2) OX=1230452 GN=bgaH PE=1 SV=2 |
| B9LW38 | 2.78e-105 | 33 | 666 | 3 | 645 | Beta-galactosidase Bga OS=Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) OX=416348 GN=Hlac_2868 PE=1 SV=1 |
| Q8GEA9 | 9.13e-96 | 32 | 690 | 1 | 644 | Beta-galactosidase BgaA OS=Thermus sp. OX=275 GN=bgaA PE=1 SV=1 |
| O69315 | 1.28e-95 | 32 | 690 | 1 | 644 | Beta-galactosidase OS=Thermus thermophilus OX=274 PE=1 SV=1 |
| O54315 | 1.28e-95 | 32 | 690 | 1 | 644 | Beta-galactosidase BgaA OS=Thermus sp. OX=275 GN=bgaA PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000482 | 0.998707 | 0.000249 | 0.000184 | 0.000182 | 0.000174 |