CAZyme Information: MGYG000001385_00387

Basic Information

• Species: Alistipes_A indistinctus
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes_A; Alistipes_A indistinctus
• CAZyme ID: MGYG000001385_00387
• CAZy Family: GH127
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
810		90763.43	6.2424

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001385	2850981	Isolate	not provided	not provided

• Gene Location: Start: 491685; End: 494117 Strand: +

Full Sequence      

MICPTLWGAPESSPLPADLTAVPFGQVTVRDRLWAPWRERMDRVTLPHCLVKTEPAVENL
RRTAHFLSGVPDRMPVRSLFLVSDLYKVMEAAAYSLQVTPDPLLEARMDSIIGWIAGAQR
SDGYMYEAHVCGIPDTAEMGSRPYERLISSHELYNMGHLYEAAVAYSRATGKDRLLAVAE
KHARHVNRAFFEGDPNYNGGRPINHISGHPEIELALCKLFGQTRDSLYLRMAQRFVAIRG
TDPPAHFTGDLSKSQEHIPLREQYEPVGHAVCAAYIYSGMADVDALCGTQHYRVPLDSIW
ENLVRTRIALTGGLGAVRGLEGFGPPYSLPNKNSYNETCASVANVLFNDRMFRSRHDGRY
FDVLECALFNGALAGINLAGDRFFYVNPLEADGLQPFNLGQKGRSSWFGCACCPPNIARL
LMQVPGLMYYHTGRDIYLTLYGSSSTEVPLADGTVAVEQTSDYPFSGESTIVLTPANPMT
FALRLRIPTWARGGEFLPGGLYTYADAASGRWTVKVNGKPVDVPLEEGFAVIDRRWRPGD
RVELSLPMQPRYVQARPEVKADVDRVAVVCGPLVYCAEEPDNGLVQRYYLSELPALRRSL
IEEGLLKGLPAVDLTASRLDTTVRLPLRLIPYYAWDNRGDLSMAVWLPRTGALAQESLPR
TEKNKVWLKEVRFTCNDDQPFRDAIFDGMTPERSHHQGYPCWTSRGCEGQFQQVEFLFTR
PRSLAGLSVYWISDARTTTLLPDSWSLEYLLDGRWLPFPRYVTDLYGLEVDQFNDVRPAG
ELVCEGLRMQIEPRSGHSVGMAEVRIDFVP

Enzyme Prediction     

EC	3.2.1.185

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	27	576	1.1e-164	0.9980916030534351

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	3.95e-140	26	576	1	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	6.54e-135	4	649	1	587	Uncharacterized conserved protein, DUF1680 family [Function unknown].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCG53293.1	0.0	41	810	1	770
QRM68944.1	2.12e-264	19	807	25	820
QTO26465.1	1.21e-263	19	807	25	820
QCQ43891.1	1.21e-263	19	807	25	820
QCQ52853.1	1.21e-263	19	807	25	820

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6EX6_A	9.56e-142	22	657	10	637	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
4QJY_A	1.05e-120	27	647	16	645	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	5.41e-116	27	647	16	645	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
3WRE_A	2.82e-95	79	649	72	658	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	3.70e-95	79	649	72	658	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	1.54e-94	79	649	72	658	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000064	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001385_00387.