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CAZyme Information: MGYG000001385_01570

You are here: Home > Sequence: MGYG000001385_01570

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes_A indistinctus
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes_A; Alistipes_A indistinctus
CAZyme ID MGYG000001385_01570
CAZy Family PL8
CAZyme Description Xanthan lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
812 MGYG000001385_2|CGC4 90421.16 5.4715
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001385 2850981 Isolate not provided not provided
Gene Location Start: 293512;  End: 295950  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001385_01570.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 399 685 4.1e-86 0.9922779922779923

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 0.0 37 756 2 693
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam02278 Lyase_8 1.06e-92 399 684 1 252
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam08124 Lyase_8_N 9.60e-86 45 359 2 323
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884 Lyase_8_C 1.35e-17 700 763 1 66
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCG54808.1 0.0 40 812 1 773
BCG53521.1 6.91e-314 18 806 15 785
BCG53520.1 2.14e-244 18 808 14 800
ALC80364.1 3.34e-203 12 803 14 779
QYR20590.1 1.43e-190 11 809 9 778

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6F2P_A 7.48e-176 33 809 2 750
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
2E24_A 6.18e-168 34 808 1 749
ChainA, Xanthan lyase [Bacillus sp. GL1]
2E22_A 6.18e-168 34 808 1 749
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
1J0M_A 1.73e-167 34 808 1 749
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
1X1H_A 9.67e-167 34 808 1 749
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 5.73e-165 34 808 26 774
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q54873 2.15e-90 68 730 322 965
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q53591 1.37e-85 31 714 246 930
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
Q59801 2.02e-78 33 684 45 694
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
P0CZ01 1.19e-72 111 769 114 757
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000003 0.000049 0.999988 0.000001 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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