CAZyme Information: MGYG000001393_03020

Basic Information

• Species: Hafnia paralvei
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Hafnia; Hafnia paralvei
• CAZyme ID: MGYG000001393_03020
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
396		43780.15	7.3482

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001393	4880992	Isolate	not provided	not provided

• Gene Location: Start: 30168; End: 31358 Strand: -

Full Sequence      

MTLSQIASDSLPADRHSRPLTIGLVAGETSGDILGAGLIRALKSLHPNARFVGVAGPLMQ
AEGCEAWFEMEELAVMGIVEVLERLPRLLKIRRELTQRFSELKPDVFVGIDAPDFNITLE
GRLKQRGIRTIHYVSPSVWAWRQKRVFKIGKATDLVLAFLPFEKAFYDKFNVPCRFIGHT
MADAMPLNPDKQAARQALGIAPDALCLALLPGSRSAEVEMLSADFLKTAMILREKYPALE
IVVPLVNAKRREQFERIKAEVAPDLTAHLLDGQARNAMYASDAALLASGTAALECMLAKC
PMVVGYRMKPFTFWLAERLVKTDYVSLPNLLARRELVQELLQHDCQPEKLAAALLPLLEG
GESTKALQKTFLELHQSIRCGADEQAADAVLSLVNQ

Enzyme Prediction     

No EC number prediction in MGYG000001393_03020.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	22	379	1.7e-141	0.9943502824858758

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
TIGR00215	lpxB	0.0	21	393	7	385	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
COG0763	LpxB	0.0	19	396	1	381	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
PRK00025	lpxB	0.0	19	396	1	377	lipid-A-disaccharide synthase; Reviewed
pfam02684	LpxB	3.65e-175	22	390	1	374	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
PRK01021	lpxB	1.39e-52	24	348	231	560	lipid-A-disaccharide synthase; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QQE43667.1	1.11e-284	1	396	1	396
AJR00454.1	9.16e-284	1	396	1	396
AMH18143.1	3.06e-282	1	396	1	396
ANC40922.1	2.31e-277	1	396	1	396
AWV45933.1	2.31e-277	1	396	1	396

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8N_A	2.22e-220	16	393	3	380	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]
5W8S_A	1.82e-219	16	393	3	380	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q667K2	9.23e-234	18	396	16	394	Lipid-A-disaccharide synthase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) OX=273123 GN=lpxB PE=3 SV=1
Q8ZH55	9.23e-234	18	396	16	394	Lipid-A-disaccharide synthase OS=Yersinia pestis OX=632 GN=lpxB PE=3 SV=1
A8GID3	3.26e-231	16	393	2	379	Lipid-A-disaccharide synthase OS=Serratia proteamaculans (strain 568) OX=399741 GN=lpxB PE=3 SV=1
C6DAJ6	2.27e-229	17	394	3	380	Lipid-A-disaccharide synthase OS=Pectobacterium carotovorum subsp. carotovorum (strain PC1) OX=561230 GN=lpxB PE=3 SV=1
B7LGP4	9.89e-226	16	393	3	380	Lipid-A-disaccharide synthase OS=Escherichia coli (strain 55989 / EAEC) OX=585055 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000049	0.000007	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001393_03020.