CAZyme Information: MGYG000001405_04076

Basic Information

• Species: Ferdinandcohnia timonensis
• Lineage: Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae_L; Ferdinandcohnia; Ferdinandcohnia timonensis
• CAZyme ID: MGYG000001405_04076
• CAZy Family: GT51
• CAZyme Description: Penicillin-binding protein 1A/1B

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
807		88714.05	4.4376

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001405	4608762	Isolate	not provided	not provided

• Gene Location: Start: 134849; End: 137272 Strand: +

Full Sequence      

MIAGATTFFVMASGAPKLDESLLKDPLSSKVYDMNGNKIYEFGAEKRTYVPLEQIPDNLK
NAVLAVEDARFYEHHGLDVIRLGGAVLANFKEGFGAEGASTISQQVIKNSFFEEGQKKLT
RKAQELWLAFQLERKYSKDEILEMYLNKIYYGVGNTYGVAKAAEIYFDKPLDELELHEAA
FIAGLGQNPGIYNPFVHPEAAEKRRNIVLTLMVRHDFISKEEADAAKKVPIETSIVESEE
QSHPIDSFMDQVKRELKESDIDVYNAGVKIYTTFDPEAQAHIDSLLANKNPDVQFPNDKL
QAGIAVVDTKTGEIRALGGGRNQAQNSRRNFALESDNQPGSTIKPILDYGPAIEYLKWST
YQQIKDEPYTYSDKTPINNFDRKYMGQITARVALAHSRNIPALKAFQEVGVTKATEFANG
LGITFDERINEAYSIGGMHGGISPLEMAGAYATFGNEGNFIKPHAVNKIVFPDNREVVLA
PEPETAMSEATAFMVTDMLKSVMDFGSGRRYDVSGLQIAGKTGTTNYSAKDIKNYNIPSG
GVPDIWFSGYTPSYTVSIWTGYSNNQEAVLPAEQSLALKLFRDIITNLSEGKEAEDFVMP
KSVVKVGVEKGSNPAKLPSEFTPKDEIVYEYFIKGTEPTQVSDKYDKLTTPSNLEVLYDQ
ETNQIKLSWAYAEGELERNSFEISVSIDEGPAKVLTTTKELTYTVPEAIPGAIYKFTVTA
VNDENPEQRSDPATNTIEVPEPAEEEIEIPLPPVTPPGNGNGNDNGNGGENDGNNNGEGN
GEGSGDGNGDEEVPVFPPVPPGNGDRQ

Enzyme Prediction     

No EC number prediction in MGYG000001405_04076.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	36	213	2.1e-64	0.9887005649717514

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	0.0	2	639	29	650	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	0.0	46	591	1	531	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009	MrcA	3.37e-149	1	666	16	790	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
TIGR02071	PBP_1b	5.49e-110	29	610	115	702	penicillin-binding protein 1B. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG4953	PbpC	9.99e-92	9	670	15	634	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QOR68963.1	0.0	1	749	1	751
APH04640.1	3.89e-293	1	750	47	791
QNG61477.1	4.70e-289	1	741	50	787
QGQ46655.1	7.63e-282	1	754	52	797
QNF30636.1	2.84e-281	1	724	52	777

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3DWK_A	6.03e-123	22	603	1	602	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A	1.43e-118	15	603	3	611	StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
2C6W_B	6.37e-73	245	607	6	378	Penicillin-BindingProtein 1a (Pbp-1a) From Streptococcus Pneumoniae [Streptococcus pneumoniae]
2C5W_B	6.55e-73	245	607	7	379	PENICILLIN-BINDINGPROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE [Streptococcus pneumoniae R6]
2ZC5_B	2.04e-72	245	607	9	381	ChainB, Penicillin-binding protein 1A [unidentified],2ZC5_D Chain D, Penicillin-binding protein 1A [unidentified],2ZC6_B Chain B, Penicillin-binding protein 1A [unidentified],2ZC6_D Chain D, Penicillin-binding protein 1A [unidentified]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P39793	5.03e-230	1	746	49	796	Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
Q04707	1.82e-133	1	607	25	644	Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q8DR59	7.10e-133	1	607	25	644	Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
Q00573	1.11e-131	1	599	25	637	Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
P38050	2.62e-97	18	646	38	644	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.846211	0.151880	0.000955	0.000280	0.000202	0.000487

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001405_04076.