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CAZyme Information: MGYG000001416_00249
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Cellulomonas massiliensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Cellulomonadaceae; Cellulomonas; Cellulomonas massiliensis | |||||||||||
| CAZyme ID | MGYG000001416_00249 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 287224; End: 288756 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 16 | 285 | 9.1e-74 | 0.9910313901345291 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1928 | PMT1 | 5.33e-18 | 12 | 239 | 26 | 225 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 1.74e-10 | 14 | 242 | 1 | 200 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG1807 | ArnT | 5.86e-09 | 10 | 184 | 7 | 163 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| COG4346 | COG4346 | 1.35e-08 | 82 | 356 | 136 | 335 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam13231 | PMT_2 | 1.53e-06 | 81 | 185 | 1 | 104 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QHT58147.1 | 1.53e-276 | 4 | 510 | 17 | 523 |
| QVI66570.1 | 7.20e-275 | 2 | 510 | 83 | 590 |
| AEE47197.1 | 1.86e-261 | 2 | 510 | 94 | 602 |
| VEH35556.1 | 1.86e-261 | 2 | 510 | 94 | 602 |
| QVI63161.1 | 1.39e-260 | 2 | 510 | 106 | 619 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6P25_A | 3.37e-06 | 1 | 242 | 45 | 252 | Structureof S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 6.63e-81 | 5 | 509 | 33 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 1.65e-79 | 5 | 509 | 39 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 1.65e-79 | 5 | 509 | 39 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 2.25e-59 | 6 | 509 | 32 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
| Q9C100 | 1.48e-06 | 14 | 254 | 62 | 276 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ogm2 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.662042 | 0.322411 | 0.009295 | 0.002331 | 0.001374 | 0.002539 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 7 | 29 |
| 104 | 121 |
| 128 | 150 |
| 155 | 174 |
| 214 | 236 |
| 263 | 285 |
| 384 | 401 |
| 406 | 423 |
| 430 | 452 |
| 472 | 494 |