CAZyme Information: MGYG000001416_00983

Basic Information

• Species: Cellulomonas massiliensis
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Cellulomonadaceae; Cellulomonas; Cellulomonas massiliensis
• CAZyme ID: MGYG000001416_00983
• CAZy Family: CBM66
• CAZyme Description: Fructose import binding protein FrcB

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
365	MGYG000001416_1|CGC17	37265	3.871

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001416	3245988	Isolate	not provided	not provided

• Gene Location: Start: 1057894; End: 1058991 Strand: +

Full Sequence      

MTHVRTRLPRFATATTALAAAGLLVSGCSSGGQTGGAPTVGADEPVGVSLIVKTTTNPFF
VAMQEGAKAAAEAADVDLTLAAGKEDGDEDSQIQAIENAISQGQQGILITPNGPAVVDAI
DRARDAGLYVIALDTPPDPADAVDITFATDNRDAGRRIGEWAAAHLDGEKATIALLDLFD
DKVVSVDYDRDQGFLQGMGIDVADENANGDEAPTGSYSGGQYEIVCNEATNGAEDGGTSA
METCLSKNPDINLVYTINEPAAYGAHQALTSAGKESGVTIVSVDGGCAGVGYVADGVIGA
TSQQYPVRMAEEGVKAIADLARTGTKPSTSAGLDFFDTGVALVTDQPADGVESITTDEAQ
KVCWG

Enzyme Prediction     

No EC number prediction in MGYG000001416_00983.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd19973	PBP1_ABC_sugar_binding-like	5.02e-119	47	344	1	285	monosaccharide ABC transporter substrate-binding protein. Periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this family function as the primary receptors for chemotaxis and transport of many sugar based solutes in bacteria and archaea. The sugar binding domain is also homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR. Moreover, this periplasmic binding domain, also known as Venus flytrap domain, undergoes transition from an open to a closed conformational state upon the binding of ligands such as lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. This family also includes the periplasmic binding domain of autoinducer-2 (AI-2) receptors such as LsrB and LuxP which are highly homologous to periplasmic pentose/hexose sugar-binding proteins.
cd01536	PBP1_ABC_sugar_binding-like	1.20e-51	48	327	2	259	periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. Periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this family function as the primary receptors for chemotaxis and transport of many sugar based solutes in bacteria and archaea. The sugar binding domain is also homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR. Moreover, this periplasmic binding domain, also known as Venus flytrap domain, undergoes transition from an open to a closed conformational state upon the binding of ligands such as lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. This family also includes the periplasmic binding domain of autoinducer-2 (AI-2) receptors such as LsrB and LuxP which are highly homologous to periplasmic pentose/hexose sugar-binding proteins.
COG1879	RbsB	1.38e-45	37	352	25	316	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain [Carbohydrate transport and metabolism].
cd06322	PBP1_ABC_sugar_binding-like	3.05e-41	46	320	2	252	periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consist of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
cd19971	PBP1_ABC_sugar_binding-like	6.36e-41	54	320	8	251	monosaccharide ABC transporter substrate-binding protein. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SDU77659.1	6.32e-154	1	365	663	1025

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5DTE_A	1.04e-17	42	306	24	272	CrystalStructure of an ABC transporter periplasmic solute binding protein (IPR025997) from Actinobacillus succinogenes 130z(Asuc_0081, TARGET EFI-511065) with bound D-allose [Actinobacillus succinogenes 130Z],5DTE_B Crystal Structure of an ABC transporter periplasmic solute binding protein (IPR025997) from Actinobacillus succinogenes 130z(Asuc_0081, TARGET EFI-511065) with bound D-allose [Actinobacillus succinogenes 130Z],5DTE_C Crystal Structure of an ABC transporter periplasmic solute binding protein (IPR025997) from Actinobacillus succinogenes 130z(Asuc_0081, TARGET EFI-511065) with bound D-allose [Actinobacillus succinogenes 130Z],5DTE_D Crystal Structure of an ABC transporter periplasmic solute binding protein (IPR025997) from Actinobacillus succinogenes 130z(Asuc_0081, TARGET EFI-511065) with bound D-allose [Actinobacillus succinogenes 130Z]
7E7M_A	1.61e-17	43	319	46	294	ChainA, D-ribose ABC transporter substrate-binding protein [Streptococcus agalactiae],7E7M_B Chain B, D-ribose ABC transporter substrate-binding protein [Streptococcus agalactiae],7E7M_C Chain C, D-ribose ABC transporter substrate-binding protein [Streptococcus agalactiae],7E7M_D Chain D, D-ribose ABC transporter substrate-binding protein [Streptococcus agalactiae]
1DRK_A	2.10e-17	48	334	4	264	PROBINGPROTEIN-PROTEIN INTERACTIONS: THE RIBOSE-BINDING PROTEIN IN BACTERIAL TRANSPORT AND CHEMOTAXIS [Escherichia coli]
2GX6_A	5.91e-17	48	334	5	265	ChainA, D-ribose-binding periplasmic protein [Escherichia coli K-12]
1DBP_A	9.95e-17	48	334	4	264	IDENTICALMUTATIONS AT CORRESPONDING POSITIONS IN TWO HOMOLOGOUS PROTEINS WITH NON-IDENTICAL EFFECTS [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q9F9B2	2.59e-99	46	365	28	341	Fructose import binding protein FrcB OS=Rhizobium meliloti OX=382 GN=frcB PE=1 SV=1
Q9I2F8	8.51e-17	48	344	37	317	D-ribose/D-allose-binding protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=rbsB PE=1 SV=1
P0A2C5	2.21e-16	48	334	29	289	Ribose import binding protein RbsB OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rbsB PE=1 SV=1
P0A2C6	2.21e-16	48	334	29	289	Ribose import binding protein RbsB OS=Salmonella typhi OX=90370 GN=rbsB PE=3 SV=1
P02925	7.59e-16	48	334	29	289	Ribose import binding protein RbsB OS=Escherichia coli (strain K12) OX=83333 GN=rbsB PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000001	0.000019	1.000014	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001416_00983.