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CAZyme Information: MGYG000001417_03099

You are here: Home > Sequence: MGYG000001417_03099

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Noviherbaspirillum massiliense
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; Noviherbaspirillum; Noviherbaspirillum massiliense
CAZyme ID MGYG000001417_03099
CAZy Family GT9
CAZyme Description ADP-heptose--LPS heptosyltransferase 2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
365 39377.33 6.7615
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001417 4171493 Isolate not provided not provided
Gene Location Start: 119866;  End: 120963  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001417_03099.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 89 327 8.4e-43 0.9466666666666667

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03789 GT9_LPS_heptosyltransferase 3.42e-46 12 350 1 275
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0859 RfaF 5.64e-34 10 350 1 330
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
pfam01075 Glyco_transf_9 2.18e-22 168 304 84 220
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
TIGR02193 heptsyl_trn_I 8.59e-16 12 303 1 290
lipopolysaccharide heptosyltransferase I. This family consists of examples of ADP-heptose:LPS heptosyltransferase I, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK10422 PRK10422 1.55e-08 185 307 176 302
lipopolysaccharide core biosynthesis protein; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QDZ27671.1 2.85e-170 1 357 1 356
QPI51158.1 2.42e-146 5 355 7 355
QOL50638.1 1.07e-139 7 353 10 372
ATQ78652.1 1.34e-139 26 356 2 330
QYF95394.1 7.00e-135 7 355 6 352

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1PSW_A 1.10e-10 12 318 2 312
Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli]
3TOV_A 8.48e-10 9 315 7 307
Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P37692 9.99e-12 12 318 2 312
ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1
P37421 1.80e-11 12 318 2 312
ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1
P45042 6.13e-09 12 304 2 298
ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000063 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001417_03099.