CAZyme Information: MGYG000001420_00600

Basic Information

• Species: Alistipes senegalensis
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes senegalensis
• CAZyme ID: MGYG000001420_00600
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
982	MGYG000001420_1|CGC11	110559.66	6.7647

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001420	3985129	Isolate	not provided	not provided

• Gene Location: Start: 777674; End: 780622 Strand: -

Full Sequence      

MTRMCVRTMVLTALLSLCGVAGAIAQISLATGKPAGSQFLLAGKSSGATLYYDSRDFEVV
KRAAGFLSQDIGLVTGRSATVRTLPAANEATIVVIGTLGHNSLIDKLVSEGRLNVDKIRG
GWEQYAVEVVERPAAGIRKALVIAGSDRRGTAYGVFSVSEAIGVSPWYWWADVPVAKKDR
LTLDVKSYRSKEPSVKYRGLFINDEDFGLKPWAAKTFEPEVGDIGPKTYSKICELLLRMK
GNYLCPAMHSCTKAFNYYPDNKLVADSLAIVMGSVHCEPLLFNNASEWDRKTMGEWNYVT
NKEGINKVLRKRVEENGAYENVYTLAMRGIHDAVMAGNLTLEEQARVLEKVFDDQRQILS
DVLGKPADQIPQAFTPYKEVLHTYEHGMKLPDDVTIVWGDDDFGYMKRLSNAEEQKRSGR
SGVYYHLSYWGPPMNFLWINTNPPVQMYTELKRAYDTTADRIWLANVGDIKPAENALSLF
LDMAWDIDAFTVENVGFYYANTLSKYFGEQHRDALQHIFDEYFSLAFARKPEHMQHHLEQ
HFAEDNYHEAERRTARYAAISAEADAIYAQLDEDSKPGFFQLVYYPVKGAALLNIAFLEA
QRNRWYAAQGRVSANQVRERVNAAIDELRKITKDYNELKDGKWRYMMTLAQGGWRDIYVP
PTKKVEPAAVPGLGVHAESETLHTGMGNFHTLPTFNPFTDKSYYVDVFNTGNGELKWSAQ
PSEPWIKLDKMAGSTPYEQRVNVSVDWDKAPKGRNLSARIAFKGAGTEKTVYVSAFNPAE
IVRDSLAGLYVEDNGVVSIDAAGFHRKFERHGITFDKIARYGFEDTVVQLGDPFAKADFY
PGLELTSNYVAPAPLDRYPMIEYDFYSFTTGPIDVYTYMVPLFPLDDEHGTRYGVMVDRS
PVYLPEAGAPYYSTLWIQSIMRNCRINKTSHMISEPGKHTVRIFAAHPGMMIQKIVIDFG
GMKYSYMGPQPTKVEAKTKSEK

Enzyme Prediction     

No EC number prediction in MGYG000001420_00600.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	38	668	1.5e-229	0.8464849354375896

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	4.91e-167	191	533	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.05e-44	790	969	2	170	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
cd14948	BACON	0.004	710	774	23	81	Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUR45611.1	0.0	14	974	8	969
QUR45612.1	0.0	19	973	16	982
BCA48102.1	0.0	39	972	33	979
QMW85894.1	0.0	39	972	33	979
AAO78620.1	0.0	39	972	33	979

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4ZMH_A	2.32e-160	41	972	16	933	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
5BY3_A	8.28e-127	59	643	39	611	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4C90_A	3.62e-118	34	662	39	658	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	1.08e-113	38	655	16	633	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	2.04e-113	38	655	15	632	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.003741	0.964043	0.030579	0.000985	0.000349	0.000274

TMHMM  Annotations     

start	end
9	31