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CAZyme Information: MGYG000001431_00052

You are here: Home > Sequence: MGYG000001431_00052

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Helicobacter pylori_BU
Lineage Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Helicobacteraceae; Helicobacter; Helicobacter pylori_BU
CAZyme ID MGYG000001431_00052
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
146 17170.79 5.5821
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001431 1602443 Isolate not provided not provided
Gene Location Start: 12219;  End: 12659  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.69

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 4 133 1.6e-46 0.4927536231884058

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 4.30e-36 3 118 133 255
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 5.08e-14 8 134 165 298
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QEF30980.1 1.67e-109 1 146 1 146
ALM80218.1 6.79e-109 1 146 1 146
QEF41305.1 1.95e-108 1 146 1 146
QEF45467.1 1.95e-108 1 146 1 146
AKE81894.1 1.95e-108 1 146 1 146

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 1.04e-21 1 133 162 302
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000044 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001431_00052.