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CAZyme Information: MGYG000001431_00172
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Helicobacter pylori_BU | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Helicobacteraceae; Helicobacter; Helicobacter pylori_BU | |||||||||||
| CAZyme ID | MGYG000001431_00172 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 32965; End: 34647 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 404 | 534 | 7.9e-20 | 0.7777777777777778 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd13401 | Slt70-like | 9.94e-51 | 386 | 539 | 1 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| pfam01464 | SLT | 1.99e-30 | 396 | 507 | 5 | 114 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
| COG0741 | MltE | 6.44e-28 | 280 | 546 | 47 | 293 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| cd16896 | LT_Slt70-like | 2.61e-22 | 390 | 535 | 3 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd00254 | LT-like | 1.69e-21 | 403 | 533 | 1 | 110 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| SMA52657.1 | 0.0 | 1 | 560 | 14 | 573 |
| QEF28284.1 | 0.0 | 1 | 560 | 1 | 560 |
| ADU81502.1 | 0.0 | 1 | 560 | 1 | 560 |
| QEF35453.1 | 0.0 | 1 | 560 | 1 | 560 |
| QEF31267.1 | 0.0 | 1 | 560 | 1 | 560 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7LAM_A | 9.22e-68 | 17 | 557 | 19 | 537 | ChainA, Lytic transglycosylase domain-containing protein [Campylobacter jejuni],7LAQ_A Chain A, Lytic transglycosylase domain-containing protein [Campylobacter jejuni] |
| 6CF9_A | 4.34e-67 | 20 | 557 | 2 | 517 | Crystalstructure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni at 2.3A resolution in I23 space group [Campylobacter jejuni],6CFC_A Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Bulgecin A [Campylobacter jejuni] |
| 6CF8_A | 4.34e-67 | 20 | 557 | 2 | 517 | Crystalstructure of Cj0843 lytic transglycosylase of Campylobacter jejuni at 1.87A resolution [Campylobacter jejuni] |
| 5MPQ_A | 2.37e-12 | 377 | 541 | 399 | 560 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 5O1J_A | 2.38e-12 | 377 | 541 | 403 | 564 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P39434 | 3.69e-09 | 403 | 541 | 495 | 630 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
| P0AGC3 | 8.49e-09 | 403 | 542 | 495 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| P0AGC4 | 8.49e-09 | 403 | 542 | 495 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000386 | 0.998988 | 0.000164 | 0.000154 | 0.000147 | 0.000140 |