CAZyme Information: MGYG000001436_01065

Basic Information

• Species: Paenibacillus_F sp000411255
• Lineage: Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_F; Paenibacillus_F sp000411255
• CAZyme ID: MGYG000001436_01065
• CAZy Family: GT51
• CAZyme Description: Monofunctional biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
816	MGYG000001436_1|CGC16	87332.44	9.2514

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001436	6290841	Isolate	not provided	not provided

• Gene Location: Start: 1208459; End: 1210909 Strand: -

Full Sequence      

MTDTEQTDKPGKKNRTTPKKKRKARKIAGFVVLGALVVVLGAGAWAAKTGIEMYRQTDLS
KLAQEPPMPLRIYDANKELITELTNSRMEYVPYSAFPKELTNAIVAVEDSRFYEHDGIDY
KGLSRALFTNVKNGEVVQGGSTITQQLAKVKLFSSEQTLERKINEAVAALKIENNYGKEQ
ILELYLNYIYYGRGAWGIERASQIYFGKNTSELTLAEAALLAGLPKSPNAYSPLNNPDKA
KERRDLVLGMMASQGKITAEERDRAQNEPIKLTENTSLSASNKYPTYVDYVIQETLDKTK
MSEQEILSAGLEIYTNLDPKVQDAAEAVYRDKKNFPGDKGGLQSSVVVLDAKTGAVKGLV
GSRSETKEFRAFNYATQLQRQPGSTIKPVVVYTPALLAGFKPQDLINDAETEFAGGYKPN
NYGHRFHGWVTMEEALAQSYNVPAVALMKEVGVEKALAFGRKAGLPLEDDDQVYGLALGG
MKYGTSPLVMAQAYTMYANGGNLAHAYAVTQVKDRSGNVILEQKTKTARVIDADTAYTMS
EMLQKVITEGSGRNARLNRDVAGKTGTTQLPDVAEFRTSSGGVIDGSKDAWFVGYTPELV
TAVWVGYPVTNREHYLTTGGDKLPAAIFQKIMSQALKGQPLTAFKAPQGYRLAGGKIQRI
NGENGKAYAAVDSRERKSGSRTRTEDSTDGEAPATPSPLPSQAPADGAGTAPGGKETPAG
TGSPPPKNGTGSVKPPVAGKEPPEGTEKPSGEATPQPSPGVKPPEGEAAPTASAKPTPKP
PAKKEEGGAAGSGVSASRPSTVPSPSPSDEGAAAGN

Enzyme Prediction     

No EC number prediction in MGYG000001436_01065.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	78	251	3.1e-69	0.9774011299435028

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	0.0	51	704	37	660	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	0.0	87	638	1	531	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009	MrcA	1.31e-168	58	712	36	795	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
TIGR02071	PBP_1b	6.75e-109	79	606	135	656	penicillin-binding protein 1B. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
TIGR02073	PBP_1c	9.05e-90	103	742	48	666	penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QAV20448.1	0.0	1	816	1	819
AEI44743.1	8.33e-257	10	669	3	664
AFH64828.2	1.75e-255	10	699	3	689
AFC32509.1	3.50e-255	10	669	3	664
AET67864.1	2.68e-190	33	650	24	637

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3ZG8_B	5.97e-119	171	644	2	469	CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B	9.03e-109	171	644	2	469	CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
4OON_A	3.53e-82	68	649	19	736	Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
3DWK_A	2.60e-80	65	661	3	610	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
3UDF_A	1.83e-79	69	640	20	720	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P38050	6.61e-131	71	635	50	597	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2
A0A0H2ZMF9	5.29e-122	33	654	54	670	Penicillin-binding protein 2a OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) OX=373153 GN=pbp2a PE=1 SV=1
Q8DNB6	5.29e-122	33	654	54	670	Penicillin-binding protein 2a OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbp2a PE=1 SV=1
P39793	4.09e-105	9	638	13	646	Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
P70997	8.45e-101	27	649	16	621	Penicillin-binding protein 2D OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpG PE=2 SV=3

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.994093	0.005166	0.000113	0.000057	0.000025	0.000560

TMHMM  Annotations     

start	end
27	46