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CAZyme Information: MGYG000001436_03730
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Paenibacillus_F sp000411255 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_F; Paenibacillus_F sp000411255 | |||||||||||
| CAZyme ID | MGYG000001436_03730 | |||||||||||
| CAZy Family | GT27 | |||||||||||
| CAZyme Description | Chondroitin synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 907685; End: 908563 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT27 | 10 | 287 | 1.4e-59 | 0.9932203389830508 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd02510 | pp-GalNAc-T | 6.38e-33 | 10 | 220 | 1 | 233 | pp-GalNAc-T initiates the formation of mucin-type O-linked glycans. UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferases (pp-GalNAc-T) initiate the formation of mucin-type, O-linked glycans by catalyzing the transfer of alpha-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to hydroxyl groups of Ser or Thr residues of core proteins to form the Tn antigen (GalNAc-a-1-O-Ser/Thr). These enzymes are type II membrane proteins with a GT-A type catalytic domain and a lectin domain located on the lumen side of the Golgi apparatus. In human, there are 15 isozymes of pp-GalNAc-Ts, representing the largest of all glycosyltransferase families. Each isozyme has unique but partially redundant substrate specificity for glycosylation sites on acceptor proteins. |
| cd02525 | Succinoglycan_BP_ExoA | 1.18e-26 | 9 | 217 | 2 | 212 | ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus. |
| pfam00535 | Glycos_transf_2 | 2.32e-25 | 10 | 171 | 1 | 164 | Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. |
| cd00761 | Glyco_tranf_GTA_type | 6.66e-25 | 12 | 204 | 2 | 156 | Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities. |
| cd04186 | GT_2_like_c | 2.29e-23 | 12 | 212 | 2 | 164 | Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QNF28463.1 | 4.80e-118 | 5 | 292 | 3 | 292 |
| AIE59841.1 | 1.90e-115 | 10 | 292 | 9 | 293 |
| QYF80448.1 | 2.17e-109 | 7 | 292 | 5 | 292 |
| ASS96799.1 | 3.40e-109 | 7 | 292 | 8 | 295 |
| UAC49115.1 | 1.29e-108 | 7 | 292 | 6 | 293 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1XHB_A | 2.53e-20 | 7 | 220 | 29 | 265 | TheCrystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1 [Mus musculus] |
| 2D7I_A | 1.96e-19 | 7 | 222 | 112 | 347 | Crystalstructure of pp-GalNAc-T10 with UDP, GalNAc and Mn2+ [Homo sapiens],2D7R_A Crystal structure of pp-GalNAc-T10 complexed with GalNAc-Ser on lectin domain [Homo sapiens] |
| 6E7I_A | 3.78e-18 | 7 | 220 | 93 | 324 | HumanppGalNAcT2 I253A/L310A Mutant with EA2 and UDP [Homo sapiens] |
| 6NQT_A | 3.96e-18 | 7 | 220 | 136 | 367 | GalNac-T2soaked with UDP-sugar [Homo sapiens],6NQT_B GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_C GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_D GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_E GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_F GalNac-T2 soaked with UDP-sugar [Homo sapiens] |
| 2FFU_A | 4.80e-18 | 7 | 220 | 66 | 297 | CrystalStructure of Human ppGalNAcT-2 complexed with UDP and EA2 [Homo sapiens],2FFV_A Human ppGalNAcT-2 complexed with manganese and UDP [Homo sapiens],2FFV_B Human ppGalNAcT-2 complexed with manganese and UDP [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P34678 | 2.87e-23 | 7 | 220 | 170 | 406 | Polypeptide N-acetylgalactosaminyltransferase 3 OS=Caenorhabditis elegans OX=6239 GN=gly-3 PE=2 SV=2 |
| Q7K755 | 4.37e-22 | 5 | 235 | 157 | 411 | Putative polypeptide N-acetylgalactosaminyltransferase 11 OS=Caenorhabditis elegans OX=6239 GN=gly-11 PE=3 SV=2 |
| Q921L8 | 8.04e-22 | 7 | 220 | 151 | 386 | Polypeptide N-acetylgalactosaminyltransferase 11 OS=Mus musculus OX=10090 GN=Galnt11 PE=1 SV=1 |
| Q6P6V1 | 1.47e-21 | 7 | 220 | 151 | 386 | Polypeptide N-acetylgalactosaminyltransferase 11 OS=Rattus norvegicus OX=10116 GN=Galnt11 PE=1 SV=1 |
| Q49A17 | 2.68e-21 | 7 | 222 | 140 | 375 | Polypeptide N-acetylgalactosaminyltransferase-like 6 OS=Homo sapiens OX=9606 GN=GALNTL6 PE=2 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000039 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |