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CAZyme Information: MGYG000001436_04113
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Paenibacillus_F sp000411255 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_F; Paenibacillus_F sp000411255 | |||||||||||
| CAZyme ID | MGYG000001436_04113 | |||||||||||
| CAZy Family | GH81 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1299862; End: 1302858 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH81 | 49 | 684 | 1.8e-159 | 0.9887459807073955 |
| CBM6 | 787 | 902 | 2.7e-36 | 0.855072463768116 |
| CBM56 | 851 | 998 | 6.7e-30 | 0.7735849056603774 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG5498 | Acf2 | 4.88e-134 | 22 | 692 | 37 | 755 | Endoglucanase Acf2 [Carbohydrate transport and metabolism]. |
| pfam17652 | Glyco_hydro81C | 3.90e-57 | 347 | 665 | 18 | 331 | Glycosyl hydrolase family 81 C-terminal domain. Family of eukaryotic beta-1,3-glucanases. Within the Aspergillus fumigatus protein, two perfectly conserved Glu residues (E550 or E554) have been proposed as putative nucleophiles of the active site of the Engl1 endoglucanase, while the proton donor would be D475. The endo-beta-1,3-glucanase activity is essential for efficient spore release. This entry represents the helical C-terminal domain. |
| cd04080 | CBM6_cellulase-like | 3.21e-39 | 782 | 902 | 1 | 143 | Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase). This family includes carbohydrate binding module 6 (CBM6) domains that are appended to several glycoside hydrolase (GH) domains, including GH5 (cellulase) and GH16, as well as to coagulation factor 5/8 carbohydrate-binding domains. CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. The CBM6s are appended to GHs that display a diversity of substrate specificities. For some members of this family information is available about the specific substrates of the appended GH domains. It includes the CBM domains of various enzymes involved in cell wall degradation including, an extracellular beta-1,3-glucanase from Lysobacter enzymogenes encoded by the gluC gene (its catalytic domain belongs to the GH16 family), the tandem CBM domains of Pseudomonas sp. PE2 beta-1,3(4)-glucanase A (its catalytic domain also belongs to GH16), and a family 6 CBM from Cellvibrio mixtus Endoglucanase 5A (CmCBM6) which binds to the beta1,4-beta1,3-mixed linked glucans lichenan, and barley beta-glucan, cello-oligosaccharides, insoluble forms of cellulose, the beta1,3-glucan laminarin, and xylooligosaccharides, and the CBM6 of Fibrobacter succinogenes S85 XynD xylanase, appended to a GH10 domain, and Cellvibrio japonicas Cel5G appended to a GH5 (cellulase) domain. GH5 (cellulase) family includes enzymes with several known activities such as endoglucanase, beta-mannanase, and xylanase, which are involved in the degradation of cellulose and xylans. GH16 family includes enzymes with lichenase, xyloglucan endotransglycosylase (XET), and beta-agarase activities. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. For CmCBM6 it has been shown that these two binding sites have different ligand specificities. |
| smart00606 | CBD_IV | 6.37e-33 | 782 | 902 | 4 | 129 | Cellulose Binding Domain Type IV. |
| pfam03422 | CBM_6 | 2.43e-27 | 787 | 902 | 1 | 123 | Carbohydrate binding module (family 6). |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QAV17866.1 | 0.0 | 1 | 998 | 1 | 1020 |
| ASS68358.1 | 0.0 | 1 | 998 | 1 | 1002 |
| SDS47552.1 | 0.0 | 1 | 998 | 1 | 1009 |
| QGG54838.1 | 0.0 | 1 | 998 | 1 | 875 |
| QJC54185.1 | 0.0 | 1 | 998 | 1 | 867 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6FOP_A | 1.32e-248 | 33 | 738 | 6 | 706 | ChainA, Glycoside hydrolase family 81 [Acetivibrio thermocellus ATCC 27405] |
| 5T4A_A | 1.42e-217 | 30 | 752 | 24 | 776 | ChainA, Glycoside Hydrolase [Halalkalibacterium halodurans C-125],5T4G_A Chain A, Glycoside Hydrolase [Halalkalibacterium halodurans C-125] |
| 5V1W_A | 1.45e-217 | 30 | 744 | 4 | 748 | ChainA, Glycoside Hydrolase [Halalkalibacterium halodurans C-125] |
| 5T4C_A | 4.00e-217 | 30 | 752 | 24 | 776 | ChainA, Glycoside Hydrolase [Halalkalibacterium halodurans C-125] |
| 5UPI_A | 4.21e-217 | 30 | 744 | 4 | 748 | ChainA, BH0236 protein [Halalkalibacterium halodurans C-125],5UPM_A Chain A, BH0236 protein [Halalkalibacterium halodurans C-125],5UPN_A Chain A, BH0236 protein [Halalkalibacterium halodurans C-125],5UPO_A Chain A, BH0236 protein [Halalkalibacterium halodurans C-125] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9UT45 | 1.36e-38 | 18 | 680 | 40 | 729 | Primary septum endo-1,3(4)-beta-glucanase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=eng1 PE=3 SV=1 |
| P53753 | 9.91e-31 | 267 | 664 | 667 | 1086 | Endo-1,3(4)-beta-glucanase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DSE4 PE=1 SV=1 |
| D4AZ24 | 3.27e-28 | 355 | 682 | 563 | 895 | Probable endo-1,3(4)-beta-glucanase ARB_01444 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=ARB_01444 PE=1 SV=1 |
| Q09850 | 7.28e-27 | 366 | 680 | 379 | 694 | Ascus wall endo-1,3(4)-beta-glucanase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=eng2 PE=1 SV=1 |
| Q5AIR7 | 5.92e-26 | 273 | 665 | 703 | 1117 | Endo-1,3(4)-beta-glucanase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=ENG1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000262 | 0.998991 | 0.000232 | 0.000176 | 0.000160 | 0.000146 |