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CAZyme Information: MGYG000001437_01288

You are here: Home > Sequence: MGYG000001437_01288

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus schleiferi
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus schleiferi
CAZyme ID MGYG000001437_01288
CAZy Family GH33
CAZyme Description Sialidase B
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
413 MGYG000001437_1|CGC17 47029.32 9.3236
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001437 2461191 Isolate not provided not provided
Gene Location Start: 1341627;  End: 1342868  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.15 3.2.1.18

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 42 413 1.7e-58 0.7602339181286549

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG4409 NanH 9.69e-106 36 409 260 636
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
cd15482 Sialidase_non-viral 8.80e-45 38 413 2 267
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13088 BNR_2 9.72e-11 267 386 85 205
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CAD7359312.1 2.16e-302 1 413 1 413
ARJ50156.1 1.42e-222 1 413 1 411
QIV99422.1 3.44e-219 29 413 10 394
QQM99222.1 3.44e-219 29 413 10 394
QDX53490.1 3.44e-219 29 413 10 394

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4XE9_A 1.65e-147 39 413 194 571
Crystalstructure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin [Streptococcus pneumoniae TIGR4],4XHB_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES [Streptococcus pneumoniae TIGR4],4XHX_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin and 2-[(3-Chlorobenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae TIGR4],4XIK_A Crystal structure of NanB sialidase from streptococcus pneumoniae in complex with DMSO [Streptococcus pneumoniae TIGR4],4XIL_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with MPD as the cryoprotectant [Streptococcus pneumoniae TIGR4],4XIO_A Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 8.0 with MPD as the cryoprotectant [Streptococcus pneumoniae TIGR4],4XJ8_A Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 5.0 in 50mM sodium Acetate with DMSO [Streptococcus pneumoniae TIGR4],4XJ9_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 5.0 in 50mM Sodium Acetate with DMSO as the cryoprotectant [Streptococcus pneumoniae TIGR4],4XJA_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 5-acetamido-2,3-difluoro-3-hydroxy-6-[1,2,3-trihydroxypropyl]oxane-2-carboxylic acid [Streptococcus pneumoniae TIGR4],4XJU_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 4-acetamido-2-fluoro-3-hydroxy-6-[1,2-dihydroxyethyl]-7,8-dioxabicyclo[3.2.1]octane-1-carboxylic acid [Streptococcus pneumoniae TIGR4],4XJW_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant [Streptococcus pneumoniae TIGR4],4XJZ_A Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 7.4 in PBS with DMSO [Streptococcus pneumoniae TIGR4]
4XMA_A 1.65e-147 39 413 194 571
Crystalstructure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin [Streptococcus pneumoniae TIGR4],4XMI_A Crystal structure of the K499G mutant of NanB sialidase from Streptococcus pneumoniae [Streptococcus pneumoniae TIGR4]
4XOG_A 1.75e-147 39 413 196 573
CRYSTALSTRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH Optactin and DANA [Streptococcus pneumoniae TIGR4]
4XYX_A 1.75e-147 39 413 193 570
NanBplus Optactamide [Streptococcus pneumoniae]
2JKB_A 3.79e-147 39 413 221 598
Crystalstructure of Streptococcus pneumoniae NanB in complex with 2, 7-anhydro-Neu5Ac [Streptococcus pneumoniae TIGR4]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q54727 2.87e-146 39 413 232 609
Sialidase B OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=nanB PE=1 SV=2
Q27701 4.39e-106 34 413 275 663
Anhydrosialidase OS=Macrobdella decora OX=6405 PE=1 SV=1
P29767 7.77e-38 38 413 383 742
Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1
P62575 5.32e-25 33 413 323 712
Sialidase A OS=Streptococcus pneumoniae OX=1313 GN=nanA PE=1 SV=1
P62576 5.32e-25 33 413 323 712
Sialidase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=nanA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.031964 0.963729 0.003368 0.000345 0.000262 0.000290

TMHMM  Annotations      download full data without filtering help

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