Species | Streptomyces albus | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Actinobacteriota; Actinomycetia; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albus | |||||||||||
CAZyme ID | MGYG000001443_05800 | |||||||||||
CAZy Family | GT39 | |||||||||||
CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 1016828; End: 1018624 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT39 | 99 | 377 | 2.8e-84 | 0.9910313901345291 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG1928 | PMT1 | 1.60e-23 | 95 | 598 | 26 | 694 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
pfam16192 | PMT_4TMC | 2.96e-16 | 405 | 595 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
pfam02366 | PMT | 2.50e-10 | 98 | 255 | 2 | 152 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
COG1807 | ArnT | 4.63e-10 | 96 | 266 | 10 | 163 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
COG4346 | COG4346 | 2.75e-09 | 166 | 258 | 136 | 227 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QID36752.1 | 0.0 | 1 | 598 | 1 | 598 |
QHF93030.1 | 0.0 | 1 | 598 | 1 | 585 |
QNF56783.1 | 0.0 | 1 | 598 | 1 | 585 |
QPP08435.1 | 0.0 | 39 | 598 | 20 | 599 |
AXK36774.1 | 0.0 | 4 | 598 | 3 | 617 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
L8F4Z2 | 5.06e-105 | 93 | 597 | 38 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
P9WN04 | 8.49e-105 | 86 | 597 | 40 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
P9WN05 | 8.49e-105 | 86 | 597 | 40 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
Q8NRZ6 | 2.34e-77 | 98 | 597 | 40 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
Q9C100 | 1.61e-07 | 96 | 332 | 61 | 262 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ogm2 PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.999959 | 0.000058 | 0.000001 | 0.000000 | 0.000000 | 0.000000 |
start | end |
---|---|
87 | 109 |
186 | 203 |
210 | 232 |
237 | 256 |
316 | 335 |
355 | 377 |
465 | 487 |
497 | 514 |
519 | 541 |
556 | 578 |
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