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CAZyme Information: MGYG000001448_00456

You are here: Home > Sequence: MGYG000001448_00456

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Dermabacter hominis
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Dermabacteraceae; Dermabacter; Dermabacter hominis
CAZyme ID MGYG000001448_00456
CAZy Family GH33
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
757 80239.19 4.535
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001448 2361290 Isolate not provided not provided
Gene Location Start: 470144;  End: 472417  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.18 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 52 389 7.9e-89 0.9473684210526315

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 1.74e-98 51 395 1 337
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
COG4409 NanH 2.57e-37 56 366 267 620
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
pfam13088 BNR_2 1.12e-25 75 379 1 280
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
pfam13859 BNR_3 4.60e-12 74 294 8 213
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
pfam10633 NPCBM_assoc 9.89e-07 414 477 3 68
NPCBM-associated, NEW3 domain of alpha-galactosidase. The English-language version of the first reference can be found on pages 388-399 of the above. This domain has been named NEW3 but its actual function is not known. It is found on proteins which are bacterial galactosidases. The domain is associated with the NPCBM family, pfam08305, a novel putative carbohydrate binding module found at the N-terminus of glycosyl hydrolases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ANP28544.1 0.0 1 754 2 752
ATH95829.1 0.0 1 509 2 510
AZQ76181.1 4.47e-232 2 625 5 622
ALE04399.1 3.83e-156 26 626 27 674
AIY02020.1 3.04e-155 26 625 27 671

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1EUR_A 8.08e-114 42 403 3 364
Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens]
1EUT_A 1.43e-113 42 494 3 450
Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens]
1WCQ_A 2.72e-112 48 494 5 446
Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens]
2BZD_A 5.36e-112 48 494 5 446
Galactoserecognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_B Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_C Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens]
1W8N_A 7.53e-112 48 494 5 446
Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q02834 1.80e-112 37 494 40 492
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
P31206 2.92e-25 64 384 203 528
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
P29767 1.72e-21 57 545 388 968
Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1
Q99519 6.21e-17 59 386 72 398
Sialidase-1 OS=Homo sapiens OX=9606 GN=NEU1 PE=1 SV=1
Q5RAF4 6.21e-17 59 386 72 398
Sialidase-1 OS=Pongo abelii OX=9601 GN=NEU1 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001005 0.997572 0.000304 0.000539 0.000332 0.000236

TMHMM  Annotations      download full data without filtering help

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