You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001457_02598
You are here: Home > Sequence: MGYG000001457_02598
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Pseudomonas_B luteola | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas_B; Pseudomonas_B luteola | |||||||||||
| CAZyme ID | MGYG000001457_02598 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipopolysaccharide heptosyltransferase 1 | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 2701601; End: 2702668 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 77 | 311 | 9.7e-49 | 0.9555555555555556 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK10964 | PRK10964 | 1.03e-163 | 1 | 297 | 1 | 299 | lipopolysaccharide heptosyltransferase RfaC. |
| TIGR02193 | heptsyl_trn_I | 1.73e-138 | 2 | 296 | 1 | 299 | lipopolysaccharide heptosyltransferase I. This family consists of examples of ADP-heptose:LPS heptosyltransferase I, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| COG0859 | RfaF | 5.68e-94 | 1 | 350 | 2 | 333 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| pfam01075 | Glyco_transf_9 | 3.80e-82 | 75 | 313 | 1 | 245 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| cd03789 | GT9_LPS_heptosyltransferase | 1.44e-60 | 2 | 327 | 1 | 270 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QEU30237.1 | 7.80e-262 | 1 | 355 | 1 | 355 |
| AYN95740.1 | 1.29e-260 | 1 | 355 | 1 | 355 |
| CDF86628.1 | 5.08e-203 | 1 | 347 | 1 | 348 |
| ANI17827.1 | 3.97e-200 | 1 | 347 | 1 | 348 |
| AMO79127.1 | 1.14e-199 | 1 | 347 | 1 | 348 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2GT1_A | 7.51e-111 | 1 | 293 | 1 | 295 | E.coli heptosyltransferase WaaC. [Escherichia coli UTI89],2GT1_B E. coli heptosyltransferase WaaC. [Escherichia coli UTI89] |
| 6DFE_A | 7.51e-111 | 1 | 293 | 1 | 295 | Thestructure of a ternary complex of E. coli WaaC [Escherichia coli],6DFE_B The structure of a ternary complex of E. coli WaaC [Escherichia coli] |
| 2H1F_A | 9.80e-111 | 1 | 293 | 1 | 295 | E.coli heptosyltransferase WaaC with ADP [Escherichia coli O6],2H1F_B E. coli heptosyltransferase WaaC with ADP [Escherichia coli O6],2H1H_A E. coli heptosyltransferase WaaC with ADP-2-deoxy-2-fluoro heptose [Escherichia coli RS218],2H1H_B E. coli heptosyltransferase WaaC with ADP-2-deoxy-2-fluoro heptose [Escherichia coli RS218] |
| 1PSW_A | 2.57e-07 | 2 | 285 | 2 | 295 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P24173 | 3.26e-110 | 1 | 293 | 1 | 295 | Lipopolysaccharide heptosyltransferase 1 OS=Escherichia coli (strain K12) OX=83333 GN=rfaC PE=1 SV=1 |
| P26469 | 1.06e-105 | 1 | 293 | 1 | 295 | Lipopolysaccharide heptosyltransferase 1 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaC PE=3 SV=2 |
| P37421 | 2.47e-08 | 1 | 285 | 1 | 295 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| P37692 | 1.40e-07 | 1 | 285 | 1 | 295 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P25742 | 1.04e-06 | 12 | 281 | 5 | 280 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000042 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |