CAZyme Information: MGYG000001461_02257

Basic Information

• Species: Bacteroides neonati
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides neonati
• CAZyme ID: MGYG000001461_02257
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
918	MGYG000001461_3|CGC3	103915.53	7.6758

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001461	5024706	Isolate	not provided	not provided

• Gene Location: Start: 336383; End: 339139 Strand: -

Full Sequence      

MKYKLATLLLGMLLTTQLPAQQPLQPNIDLSGMWRFQLDPMGFGKTPGSELYLDKLSETI
MLPGSTDQGGKGIKNSARYVDRLSRKFEYQGAAWYQREVVIPTAWAGKEIYLDLERCHWE
TTVYVDGKLVGMDERLSTPNRFLMTPLLTPGTHTLTLCVDNRLKYPMDQWAHGTTEHTQT
NWNGIVGRMALQVKEKAHIQQVKVSTDVPAKQIEVAVKLSSLKAGQKGRLDLNIREKNSS
KVIATRSVEIDSLSAASPIRQTLSMGNGMKCWDEFSPNLYELDAVWNVGETQDTQTVVYG
MRSVEQGKHHIRLNGRDIHLRGVLDCAVFPLTGYPSVDVADWKRIFSTVKEYGMNHVRFH
SWCPPKAAFTAADELGLYLQAELPMWIKDVGQYPARRDFFEKEMYAILDEYGNHPSFILM
CNGNENEGDFAVLEDLVKKAQAYDSRRLYSASTARTHTASDQYYVSHVTSKGWITTYEGK
PSTDWDLCKQSDIDVPVIAHETGQRCMYPNFEEIKKYTGVLEPRNFEVFRERLTKNGMLH
QADDFFRATGAHTVLQYKEVNESLLRTNNSGGFQLLGLADFPGQGSAFVGILDAFWESKG
LVTPEKYRESCAPTVLLARLSKRTYRAGEKFRPKLELYHYGEKAIKAQKLNWTLVDEAGV
AYRKGSCAVRTIQPARVDSLGVVEVMLDGIDTARKLTLKAELAGVKNEWDIWVYPQSTAT
VSEGFLYTRSWNEEAKRWLSEGKNVLLVPEKAEGRKARFASHFWNPIMFNWNPMIVGTLI
RNQHPAFGQFPTREYADWQWFDVLNGSTALELNNLKEITPIIQSIDSYETNQKLGIAFEA
KVGNGNLFVLCIDPEKNIDKRLAAQQLLVSVKQYVASAAFLPEKSLQLYEVDALFPAVVQ
QKSDTGKTNQAIQQLLNK

Enzyme Prediction     

No EC number prediction in MGYG000001461_02257.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	23	476	5.4e-74	0.5132978723404256

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	3.77e-22	19	448	4	428	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	4.56e-20	29	322	14	296	beta-D-glucuronidase; Provisional
PRK10340	ebgA	8.07e-13	95	448	113	471	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02837	Glyco_hydro_2_N	1.06e-10	30	170	4	154	Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.
pfam00703	Glyco_hydro_2	2.00e-06	197	302	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ANQ59584.1	0.0	2	918	9	923
QCT77449.1	0.0	2	918	9	923
CAH06599.1	0.0	2	918	9	923
QUU05975.1	0.0	2	918	9	923
CBW21485.1	0.0	2	918	9	923

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6D89_A	1.81e-15	30	452	39	443	Bacteroidesuniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis],6D89_B Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis],6D89_C Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis],6D89_D Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis]
7SF2_A	5.42e-15	29	457	41	463	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_E Chain E, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_F Chain F, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
7VQM_A	1.55e-13	21	508	1	504	ChainA, GH2 beta-galacturonate AqGalA [Aquimarina sp.],7VQM_B Chain B, GH2 beta-galacturonate AqGalA [Aquimarina sp.],7VQM_C Chain C, GH2 beta-galacturonate AqGalA [Aquimarina sp.],7VQM_D Chain D, GH2 beta-galacturonate AqGalA [Aquimarina sp.]
6D1N_A	8.11e-13	87	452	103	451	Apostructure of Bacteroides uniformis Beta-glucuronidase 1 [Bacteroides uniformis],6D1N_B Apo structure of Bacteroides uniformis Beta-glucuronidase 1 [Bacteroides uniformis],6D41_A Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone [Bacteroides uniformis],6D41_B Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone [Bacteroides uniformis],6D6W_A Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D6W_B Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D6W_C Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D6W_D Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D7F_A Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_B Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_C Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_D Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_E Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_F Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis]
6D1P_A	9.51e-10	89	434	86	439	Apostructure of Bacteroides uniformis beta-glucuronidase 3 [Bacteroides uniformis str. 3978 T3 ii],6D1P_B Apo structure of Bacteroides uniformis beta-glucuronidase 3 [Bacteroides uniformis str. 3978 T3 ii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P26257	2.26e-12	89	447	52	411	Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1
A4W7D2	7.31e-11	123	426	154	464	Beta-galactosidase OS=Enterobacter sp. (strain 638) OX=399742 GN=lacZ PE=3 SV=1
A3FEW8	1.65e-10	123	426	154	464	Beta-galactosidase OS=Enterobacter agglomerans OX=549 GN=lacZ PE=1 SV=2
P05804	2.70e-07	19	165	4	140	Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2
O97524	1.92e-06	19	425	30	450	Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000233	0.999098	0.000194	0.000157	0.000142	0.000137

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001461_02257.