CAZyme Information: MGYG000001461_03956

Basic Information

• Species: Bacteroides neonati
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides neonati
• CAZyme ID: MGYG000001461_03956
• CAZy Family: GH2
• CAZyme Description: Evolved beta-galactosidase subunit alpha

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1337		150045.63	6.7697

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001461	5024706	Isolate	not provided	not provided

• Gene Location: Start: 66191; End: 70204 Strand: -

Full Sequence      

MRKLTLSLVLCSMVSLCFAQKKPLDGFNYASITSPTGNEWESPQSLALNKEQPRAWFFSF
QDAASARKVLPENSKYWLSLNGNWKFNWAPDPDSRPKDFYQTTFDVSNWDNIPVPSSWNI
YGIQKDGSLKYGVPIYVNQPVIFQHKVQVDDWRGGVMRTPPTNWTTYKHRNEVGSYRRDF
DIPQDWDGREVFISFDGVDSFFYLWINGQYVGFSKNSRNTANFNITPYLQKGKNTIAAEV
YRSSDASFLEAQDMFRLPGIFRTVALYSTPKVQVSDLVVIPDLDETYTNGSLAITADVRN
FGKKAAKGYRIDYTLYANKLYSDENTPVTNAVASASVQLVNPKMTVTTEKTIVNVQAPHK
WSAEYPYLYTLLAELKDKKGRTLEAVSTTVGFRKVEIKDTPASADEFGLAGRYYYVNGKT
VKLKGVNRHETNPGVGHAITREMMEKEVMLMKRANINHVRNSHYPDDPYWYYLCNKYGLY
LEDEANIESHQYYYGAASLSHPIEWKEAHVARVMEMVHANVNNPSIVIWSLGNEAGPGKN
FVAAYDALKAFDTSRPVQYERNNDIVDMGSNQYPSIGWMRGAVKGGYNIKYPFHVSEYAH
SMGNACGNLVDYWEAIESTNFFCGGAIWDWVDQAMYNYDKKTGERYLAYGGDFGDTPNDG
QFVMNGIVFADLEPKPQYYEVKKVYQHIAVKAIDVQKGLFEVFNKYYFKDLSEYEVRWAL
YENGKEVQAGIAPINKVAPRQRTTISLPYSFGQLKNESEYFVKVQFLLKENMPWADKQFA
QAEEQILIKEASDRPSISTVSGSKAEVTTSNDLVTIKGNGSEATFDKKTGTIYRLTYGNE
TIISDGNGPKLDALRAFTNNDNWFYSPWFENGLHNLKHVATGYSMMTKEDGTVVLSFSVE
SQAPNAAKILGGTSSGKSSIQELTDKKFGNADFKFTTNQVWTVYKDGSIELQSSITSNQP
SLVLPRLGYVMRVPQQYENFTYYGRGPIDNYADRKTGQFIEQHKNTVTGEFVNFPKPQDM
ANHEDVRWCALTNKAGNGAVFVATDRLSVSALPYSALDLILASHPYQLPAVGDTYLHLDA
AVTGLGGNSCGQGGPLEQDRVFANHHNMGFIIRPATKDLAATANVAPAGEMPLSITRNRA
GAVSITSPKAGAVICYTIDKSKMKTYDAPIALRNGGTITAWFKDAPYIKANITFEKIESI
QTEVIYASSEESDGGEAKNLTDGDPNTIWHTMFSVTVAKHPHWVDLDAGEVKSIKGFTYL
PRQNSSNGNVKDYTIHISQDGKEWGEPIAKGTFKGDLKEKKVVFDQPVKARYIRFTALSE
QRGQDYASGAEITILAE

Enzyme Prediction     

No EC number prediction in MGYG000001461_03956.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	68	1000	1.4e-214	0.9720744680851063
CBM32	1207	1332	1.7e-27	0.9193548387096774

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK10340	ebgA	0.0	38	1114	2	999	cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525	lacZ	0.0	38	1087	15	999	beta-galactosidase.
COG3250	LacZ	6.86e-137	79	998	14	804	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam02836	Glyco_hydro_2_C	6.86e-85	414	690	8	302	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
smart01038	Bgal_small_N	9.26e-82	817	1112	1	272	Beta galactosidase small chain. This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBW23708.1	0.0	1	1337	1	1341
ANQ61423.1	0.0	1	1337	1	1341
AKA52894.1	0.0	1	1337	1	1341
QUU03905.1	0.0	1	1337	1	1341
CAH08900.1	0.0	1	1337	1	1341

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6S6Z_A	3.96e-185	39	1121	3	993	Structureof beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_B Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_C Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_D Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_E Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_F Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_G Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_H Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8]
6SD0_A	4.07e-185	39	1121	4	994	Structureof beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_B Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_C Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_D Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8]
3DEC_A	3.20e-184	39	1093	6	976	ChainA, Beta-galactosidase [Bacteroides thetaiotaomicron VPI-5482]
3BGA_A	1.05e-179	39	1093	9	980	Crystalstructure of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482 [Bacteroides thetaiotaomicron VPI-5482],3BGA_B Crystal structure of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482 [Bacteroides thetaiotaomicron VPI-5482]
3MUY_1	1.34e-122	39	1088	15	996	Chain1, Beta-D-galactosidase [Escherichia coli K-12],3MUY_2 Chain 2, Beta-D-galactosidase [Escherichia coli K-12],3MUY_3 Chain 3, Beta-D-galactosidase [Escherichia coli K-12],3MUY_4 Chain 4, Beta-D-galactosidase [Escherichia coli K-12]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O52847	1.08e-195	39	1114	19	1033	Beta-galactosidase OS=Priestia megaterium (strain DSM 319 / IMG 1521) OX=592022 GN=bgaM PE=3 SV=1
Q56307	2.23e-184	39	1121	4	994	Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2
P06864	6.87e-155	38	1126	2	1011	Evolved beta-galactosidase subunit alpha OS=Escherichia coli (strain K12) OX=83333 GN=ebgA PE=1 SV=4
Q9K9C6	1.77e-153	46	1111	16	1008	Beta-galactosidase OS=Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) OX=272558 GN=lacZ PE=3 SV=1
A1SWB8	4.89e-142	39	1088	12	1008	Beta-galactosidase OS=Psychromonas ingrahamii (strain 37) OX=357804 GN=lacZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000802	0.946500	0.051941	0.000260	0.000245	0.000227

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001461_03956.