CAZyme Information: MGYG000001472_02047

Basic Information

• Species: Oceanobacillus jeddahense
• Lineage: Bacteria; Firmicutes; Bacilli; Bacillales_D; Amphibacillaceae; Oceanobacillus; Oceanobacillus jeddahense
• CAZyme ID: MGYG000001472_02047
• CAZy Family: GT51
• CAZyme Description: Penicillin-binding protein 4

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
836	MGYG000001472_2|CGC7	93369.13	4.0465

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001472	5388095	Isolate	not provided	not provided

• Gene Location: Start: 504603; End: 507113 Strand: -

Full Sequence      

MSIMKEKLQRFFNTVKNWWKKGFIQQTSRITYDVVWNIILFVIVIGGIGGIFAGGIGLGY
FASLVHDEPLRSEASMADDIYNYSETSSIYFANDVYLGDIRSDLYREEVELDHISPTLLD
AVVATEDEYFHEHNGVVPKAILRATAQEFLNSSVQTGGSTLTQQLIKNQILTDEVSFDRK
AKEILLAMRLENYFTKDEIMEAYLNIIPYGRNASGRNIAGIQTASEGIFGVEASELTLPQ
AAYLAGLPQSPSGYTPFTSAGELKSEEELQPGIKRMKTVLNRMHDMEFITDEELEEAVNY
DIAGDFTNPVPSSRDKYPYVTYEVEKRTKDIIQEMLMEEDGVSEEDLEEDDDLRAEYIER
AEKELRDGGYQIHTTINKDIYDAMQEAAQDYSDYGYARTFTATNSDGEEYEVTQEIQTGA
IMVENNTGKIISFIGGRGFDEDHQVNFATDTRRSIGSTIKPLLDYAPAMEEGVIQPGTPI
ADYPRSFANGSFDLSNYGGGNYGLVSARTALANSYNIPAVDTYMQIIDDDPAAEYLEKMG
VTSLTPGDHVQPALSIGATDNGISVEENVNAFSTFGNNGKFADAYMIDKITDANGDVIYE
HETEPVEVFSPETTYLTVDMMRDVIDNGTGNFVNSQLQNTNVDWAGKTGTSNDYHDAWFV
ATNPNVTFGTWIGYETPASINHSYHLSYSQRNMKLWAEVINAAAQVDPVLVTPETNFERP
DGVVERSYCAVSGMLPSDLCEDVGLVKTELFDSRYVPTEEDNSLMRGSRRVLESDDDGNS
FSRSNGIMFNPDWLKENGYDEMDDFSMLYPKTERDKWLRIGIPASMSSSSSDDDDD

Enzyme Prediction     

No EC number prediction in MGYG000001472_02047.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	105	284	6.5e-56	0.9322033898305084

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	5.88e-161	86	762	55	660	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	8.64e-148	105	705	1	530	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009	MrcA	2.17e-110	106	742	67	752	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
COG4953	PbpC	1.40e-79	101	797	53	648	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
TIGR02071	PBP_1b	3.42e-74	106	715	147	694	penicillin-binding protein 1B. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BAC14175.1	0.0	4	824	1	826
AVQ99658.1	0.0	5	825	4	830
AIF43181.1	0.0	5	824	4	832
APC47999.1	0.0	5	824	4	832
API90861.1	0.0	9	827	26	853

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2JE5_A	5.21e-130	55	736	3	665	StructuralAnd Mechanistic Basis Of Penicillin Binding Protein Inhibition By Lactivicins [Streptococcus pneumoniae R6],2JE5_B Structural And Mechanistic Basis Of Penicillin Binding Protein Inhibition By Lactivicins [Streptococcus pneumoniae R6]
3DWK_A	2.73e-54	87	737	8	608	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2FFF_B	1.44e-53	317	736	2	400	OpenForm of a Class A Transpeptidase Domain [Streptococcus pneumoniae]
2JCH_A	1.73e-53	357	736	47	408	Structuraland mechanistic basis of penicillin binding protein inhibition by lactivicins [Streptococcus pneumoniae R6]
2XD1_A	2.57e-53	317	736	41	439	ACTIVESITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS [Streptococcus pneumoniae R6],2XD1_B ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS [Streptococcus pneumoniae R6]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7GHV1	9.15e-74	32	762	13	700	Penicillin-binding protein 1A OS=Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) OX=441772 GN=pbpA PE=3 SV=1
A5I6G4	2.50e-73	32	762	13	700	Penicillin-binding protein 1A OS=Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) OX=441771 GN=pbpA PE=3 SV=1
A7FY32	2.50e-73	32	762	13	700	Penicillin-binding protein 1A OS=Clostridium botulinum (strain ATCC 19397 / Type A) OX=441770 GN=pbpA PE=3 SV=1
P40750	1.27e-72	73	703	49	623	Penicillin-binding protein 4 OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpD PE=1 SV=2
Q0TNZ8	5.83e-68	20	740	14	697	Penicillin-binding protein 1A OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=pbpA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999480	0.000526	0.000002	0.000002	0.000001	0.000014

TMHMM  Annotations     

start	end
34	56