logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001484_00507

You are here: Home > Sequence: MGYG000001484_00507

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Nigerium massiliense
Lineage Bacteria; Actinobacteriota; Actinomycetia; Propionibacteriales; Propionibacteriaceae; Nigerium; Nigerium massiliense
CAZyme ID MGYG000001484_00507
CAZy Family GT39
CAZyme Description putative dolichyl-phosphate-mannose--protein mannosyltransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
551 MGYG000001484_2|CGC1 60428.17 8.4501
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001484 2934258 Isolate not provided not provided
Gene Location Start: 226561;  End: 228216  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001484_00507.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 63 328 6.4e-75 0.9820627802690582

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1928 PMT1 1.91e-27 58 551 26 694
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam02366 PMT 6.29e-17 62 280 3 195
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG1807 ArnT 6.52e-14 62 360 13 272
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
COG4346 COG4346 3.96e-12 128 280 136 255
Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].
pfam13231 PMT_2 2.01e-10 127 303 1 148
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SDU97223.1 2.49e-255 21 551 10 542
QDP97963.1 1.12e-252 39 551 38 556
SDR91313.1 4.64e-251 32 551 25 543
SDS30637.1 3.79e-249 31 551 12 539
SDD91692.1 9.63e-247 44 551 8 518

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WN04 4.65e-104 49 550 37 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 4.65e-104 49 550 37 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
L8F4Z2 3.53e-98 49 550 31 515
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
Q8NRZ6 8.54e-75 55 550 37 519
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1
F1Q8R9 2.24e-06 125 317 113 309
Protein O-mannosyl-transferase 2 OS=Danio rerio OX=7955 GN=pomt2 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999845 0.000165 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
53 75
147 169
176 193
198 217
268 287
307 329
428 447
475 497
510 532