| Species | Mobilicoccus massiliensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Dermatophilaceae; Mobilicoccus; Mobilicoccus massiliensis | |||||||||||
| CAZyme ID | MGYG000001486_01173 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipopolysaccharide core heptosyltransferase RfaQ | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 296312; End: 297355 Strand: + | |||||||||||
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 1.76e-48 | 3 | 336 | 1 | 275 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 8.81e-44 | 1 | 339 | 1 | 329 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| pfam01075 | Glyco_transf_9 | 1.32e-20 | 74 | 320 | 2 | 245 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| PRK10422 | PRK10422 | 8.30e-12 | 2 | 336 | 6 | 339 | lipopolysaccharide core biosynthesis protein; Provisional |
| PRK10964 | PRK10964 | 0.007 | 246 | 287 | 243 | 284 | lipopolysaccharide heptosyltransferase RfaC. |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| VEI49881.1 | 3.76e-147 | 1 | 339 | 1 | 345 |
| VEH43016.1 | 3.76e-147 | 1 | 339 | 1 | 345 |
| QCY33179.1 | 3.76e-147 | 1 | 339 | 1 | 345 |
| QCU78080.1 | 9.94e-137 | 1 | 335 | 1 | 340 |
| QGQ19459.1 | 1.64e-136 | 1 | 342 | 1 | 344 |
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9R9D5 | 1.31e-06 | 184 | 342 | 173 | 333 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000034 | 0.000004 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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