logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001490_01252

You are here: Home > Sequence: MGYG000001490_01252

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bifidobacterium catenulatum
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Bifidobacterium; Bifidobacterium catenulatum
CAZyme ID MGYG000001490_01252
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
406 MGYG000001490_1|CGC13 43161.29 6.5675
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001490 2079525 Isolate not provided not provided
Gene Location Start: 1423088;  End: 1424308  Strand: -

Full Sequence      Download help

MAHGVPGRRG  LSSYIMSNQK  HIVLAGGGTA  GHVNPLLAVA  HVIRELEPDA  DIAVVGTAVG60
LEHELVPQAG  FELETIEKVP  FPRRPNMAAL  KFPAQWKAET  AKVRDILTRH  EAQVVVGFGG120
YTSAPVYAAA  HKMGIPIAMH  EQNARAGMAN  KLGARWASMI  GTAYAQTGLK  PRKGVETERV180
GLPLRAEIAA  IAEGMEHDRA  ATRQTAAAQL  GVDPNRPLVV  VTGGSLGAVN  VNRAVAASAK240
ELLEHAQVIH  LTGKDKDDEV  RSLVSVSAGE  QVLGGLGSEH  VNDGDYRVAP  YLERIDLAFA300
CADLIICRSG  AGTVSELTAL  GLPAIYVPLP  IGNGEQRFNA  QPVVDAEGGL  MVADADFTSE360
WVKRHVPNLL  ADSDALARYG  DNAWKYGIRD  AAEVMARRVL  SMIDER406

Enzyme Prediction      help

No EC number prediction in MGYG000001490_01252.

CAZyme Signature Domains help

Created with Snap20406081101121142162182203223243263284304324345365385219391GT28
Family Start End Evalue family coverage
GT28 219 391 1.5e-46 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap2040608110112114216218220322324326328430432434536538520403murG21396GT28_MurG22401MurG20396murG218395Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 1.68e-131 20 403 2 355
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 6.44e-112 21 396 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.64e-91 22 401 3 353
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 7.83e-88 20 396 1 345
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 3.77e-35 218 395 1 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap204060811011211421621822032232432632843043243453653851406BAR02175.1|GT281406QGM63077.1|GT281406BAQ29543.1|GT2816406AIZ14901.1|GT2816406BAR03946.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
BAR02175.1 1.94e-292 1 406 9 414
QGM63077.1 4.21e-285 1 406 1 406
BAQ29543.1 4.21e-285 1 406 1 406
AIZ14901.1 1.36e-275 16 406 1 391
BAR03946.1 1.36e-275 16 406 1 391

PDB Hits      download full data without filtering help

Created with Snap20406081101121142162182203223243263284304324345365385153991F0K_A173607D1I_A213833S2U_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1F0K_A 3.15e-40 15 399 1 350
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 8.24e-33 17 360 7 324
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 2.90e-31 21 383 4 335
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits      download full data without filtering help

Created with Snap2040608110112114216218220322324326328430432434536538516405sp|A1A2E9|MURG_BIFAA21404sp|Q8CY50|MURG_BIFLO21404sp|B3DQN1|MURG_BIFLD21404sp|B7GQ78|MURG_BIFLS23406sp|B0RIJ3|MURG_CLAMS
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A1A2E9 3.69e-247 16 405 1 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) OX=367928 GN=murG PE=3 SV=1
Q8CY50 3.60e-196 21 404 7 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum (strain NCC 2705) OX=206672 GN=murG PE=3 SV=1
B3DQN1 3.60e-196 21 404 7 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum (strain DJO10A) OX=205913 GN=murG PE=3 SV=1
B7GQ78 4.18e-195 21 404 7 390
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) OX=391904 GN=murG PE=3 SV=1
B0RIJ3 2.78e-105 23 406 5 359
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) OX=31964 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001490_01252.