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CAZyme Information: MGYG000001514_03627

You are here: Home > Sequence: MGYG000001514_03627

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Paenibacillus_A ihumii
Lineage Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_A; Paenibacillus_A ihumii
CAZyme ID MGYG000001514_03627
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
749 MGYG000001514_12|CGC38 84505.2 5.0821
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001514 5923787 Isolate not provided not provided
Gene Location Start: 2288393;  End: 2290642  Strand: -

Full Sequence      Download help

MNVNGTEGAD  VNTAHLNAAD  LNASGLSAPG  KDKAPLLFSL  LNLQAPELAD  VAEAVRQNRK60
DEALLALHRY  YRERQVPGCR  WTTEETAQIA  EYVKKHCADE  VAAVMRTADE  VVGQTFLFQF120
PWDMERTQVP  VTFEEAIDWH  YIPDIDPEWA  YMLNRHRYWV  ALGQAYAMTG  DDKYAAAFCR180
QLEAWIDSNP  VPEAPTGDNL  AWRTIEAGLR  GSNWIKTLRY  VWDCPQLTPA  LLAKLLASLA240
EHAQYLAAAF  TSWKKISNWG  VLETSGLLQI  ALFFPEFAAA  GQWRSLAEQR  LKETAQIQVM300
ADGIHWEQSP  TYHHEVMSCY  LDCIYFAEIN  RLKLDEGFCG  KVCEMALASL  YWAKPNHRQP360
MFGDSDDNDV  RSLLTFAAAL  FKDETLRFGA  NLRMDYDSAW  LLGIEGIRSY  DRLASAEPQE420
VSHGFIHSGH  YVMRSGWSER  DLYMYFHCGP  LGGGHGHADL  LHIDLYAYGK  EFLTDLGRYN480
YSDHTPLRKA  LKESAAHNTT  TVDGLGFTEI  ADTWSYHRIA  GPLGSKWISR  PAYDYVEGSH540
DGYLQLDDPV  LADRRIIFIK  PYYWLLVDRF  RSKDAHVFRQ  HFHFVPGVID  LEEGSLVCLT600
NHKDEANLLI  IPVFGTEENG  HGLSAEITEG  VLSREYNLLE  SNHQVTYSRS  GSGLTTMMQV660
LYPLRPGMAD  RPEVSKIPVF  RHTGEQVDDE  QAEACRIAHP  ELDGEHILVV  SHRAPSGQFD720
SYVVDGVQIF  GEVVLISGTA  EERTITVIN749

Enzyme Prediction      help

No EC number prediction in MGYG000001514_03627.

CAZyme Signature Domains help

Created with Snap3774112149187224262299337374411449486524561599636674711428569PL12
Family Start End Evalue family coverage
PL12 428 569 1.3e-41 0.9927536231884058

CDD Domains      download full data without filtering help

Created with Snap377411214918722426229933737441144948652456159963667471138388Hepar_II_III_N422656Hepar_II_III
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 2.24e-52 38 388 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 3.97e-29 422 656 6 230
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Created with Snap37741121491872242622993373744114494865245615996366747111749AZS15931.1|PL1237748SMF90844.1|PL1237749AIQ73161.1|PL1237749AWV32504.1|PL1237749AIQ34533.1|PL12
Hit ID E-Value Query Start Query End Hit Start Hit End
AZS15931.1 0.0 1 749 1 724
SMF90844.1 0.0 37 748 13 719
AIQ73161.1 0.0 37 749 13 720
AWV32504.1 0.0 37 749 13 720
AIQ34533.1 0.0 37 749 13 719

PDB Hits      download full data without filtering help

Created with Snap3774112149187224262299337374411449486524561599636674711376735JMD_A386754MMH_A386754MMI_A376725JMF_A355684FNV_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5JMD_A 4.97e-43 37 673 18 623
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
4MMH_A 1.08e-42 38 675 10 605
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4MMI_A 1.08e-42 38 675 10 605
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
5JMF_A 7.39e-42 37 672 18 622
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4FNV_A 1.30e-29 35 568 47 565
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Created with Snap377411214918722426229933737441144948652456159963667471138675sp|Q59289|HEPC_PEDHD37688sp|C7EXL6|HEPC_BACSE35568sp|Q89YR9|HEPC_BACTN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q59289 6.98e-42 38 675 34 629
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
C7EXL6 1.84e-41 37 688 29 652
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q89YR9 7.12e-29 35 568 47 565
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000046 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001514_03627.