CAZyme Information: MGYG000001524_01146

Basic Information

• Species: RUG013 sp001486445
• Lineage: Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; RUG013; RUG013 sp001486445
• CAZyme ID: MGYG000001524_01146
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
357	MGYG000001524_9|CGC3	40303.73	5.6898

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001524	2090171	Isolate	not provided	not provided

• Gene Location: Start: 716042; End: 717115 Strand: -

Full Sequence      

MDGTPLVSIVMPAYGVEAYIGKAIACIQAQTIVYWELIVVDDASPDRSAAIAEAAAAEDP
RITVLHHGQNQGLSGARNTGMAHACGTYLWFCDPDDTYDSDLLGCAVSALKRTEAQVAVF
GVREEYYNAKGAFQYENVVQPEPGACLSAERVHGRMLQLERETCYGYAWNKVYDRAFLAS
TGATFENVKLIEDITFNVAVFDHVDRMVVLDRAPYRYARRIDDNLTNKFLPDYFELHERR
IQMLFDQQQAWGTLDDDARAILGSLYARYVLSALERNFDPRAQMRSADRAKWCERVFSSS
LYNELIPYAQAEDSRALAEALKPLQTKDVKRTLQLARVIHIARDKFLPLFTKIKSGR

Enzyme Prediction     

No EC number prediction in MGYG000001524_01146.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	8	137	5.4e-33	0.7647058823529411

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00535	Glycos_transf_2	2.65e-28	8	123	1	116	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd00761	Glyco_tranf_GTA_type	1.40e-25	9	122	1	114	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
COG0463	WcaA	2.54e-23	4	241	2	229	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
PRK10073	PRK10073	5.71e-21	1	97	2	97	putative glycosyl transferase; Provisional
cd04184	GT2_RfbC_Mx_like	4.90e-18	5	112	1	110	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ANE22368.1	2.30e-146	5	357	6	358
AWY97564.1	1.13e-111	5	357	4	356
QEI32679.1	1.51e-106	5	357	3	355
QRT31240.1	1.51e-106	5	357	3	355
QHB22014.1	1.51e-106	5	357	3	355

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3BCV_A	4.14e-17	5	217	5	224	Crystalstructure of a putative glycosyltransferase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3BCV_B Crystal structure of a putative glycosyltransferase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343]
5HEA_A	3.74e-15	1	119	1	118	CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P71059	8.83e-24	5	226	3	219	Uncharacterized glycosyltransferase EpsJ OS=Bacillus subtilis (strain 168) OX=224308 GN=epsJ PE=2 SV=1
A0A0H2URH7	1.78e-14	7	244	7	245	Glycosyltransferase GlyA OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=glyA PE=3 SV=1
P71057	2.09e-12	4	185	3	176	Putative glycosyltransferase EpsH OS=Bacillus subtilis (strain 168) OX=224308 GN=epsH PE=2 SV=1
Q57022	3.89e-12	5	103	4	102	Uncharacterized glycosyltransferase HI_0868 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=HI_0868 PE=3 SV=1
P46918	1.15e-11	8	96	11	101	Minor teichoic acid biosynthesis protein GgaB OS=Bacillus subtilis (strain 168) OX=224308 GN=ggaB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000073	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001524_01146.