CAZyme Information: MGYG000001542_02066

Basic Information

• Species: Paenibacillus_A sp900069005
• Lineage: Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_A; Paenibacillus_A sp900069005
• CAZyme ID: MGYG000001542_02066
• CAZy Family: GH39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1109	MGYG000001542_32|CGC3	122814.85	4.7471

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001542	5846629	Isolate	not provided	not provided

• Gene Location: Start: 77147; End: 80476 Strand: +

Full Sequence      

MKRISFVIVLLLVTQMSLLNGPVQAFSEEMAGKMAFAADDLNYLISDFEQESDNWLFAYG
DAPEVKGSFNVVESAESYAGNYMGQIKADFSQRPTGSPYASIKKEVDELDIEQLKFWVKT
SDLKSLRIRTTDSTGQTFQQRIELQNTADWQQVAVSEMGSKSFTYWNGANDGVWHKPAMA
ITILFDRFDIKNTSLTATLLVDQMTAQIGDWLPDLKIQQTALGNIFLDHEPNDFVIRTSR
PAVNWVAYDIYGAQVASGSKATNAGEARITVPFSKLGYFTLEVSAEQPGSRPLVRRTSYA
TISSALPPGNGESPFGVSTHLNRTAFGWSKELSKLVRYMGASFVRDGVEWSSIEKQKGVY
TFAPSPDDYMQKLAENDLKLLFVAAFNNPFYDNNGTPYTDAGRKGLAEYAKAYVEKYKDQ
LIGFNVYNEFNGGFGKRGNSPANSQPDYYFKLLKETYNRVKPAYPDVPVVGIVSGGIDLD
WIEGVLKGVGEGEDKNAGLKYLDAVSIQNYMDPNDPDNVFVKLEGLKTLIKQYNDGKLVP
IWVTEFGSPTHQSAKGVDEKTQANYLPRGFVTGLGLGVERMSWYDFMNDGIRADYNEDNF
GLVRYKDDPMGAYTPKPAYVSYAAMSRQLAGATFEESEQFGYPIKSNLFTKGGEALRVVW
AQSEVQAVIKTESNLEITDFMGNTEIYTPHNGKIYMTITGEPFYIKGNITRIVKDNTFAV
AGEQTAIGDPHTFTVTVKNDSLPQLALSAKMEGNSYSIVAEQGQPEVLSLTVDEIREGFR
AVSIHLLDEAGNRIGKLQHEVLTGVPQKVTVRPAMQQNDGQYSQMLNVDVENFRQATDLT
VSRVTWRVGEQSGQEHVNMIVQSGSKQQFSIPLSRVALGEDLSASIRVEFAEQEPYVYDG
NFSFNPVTRGTIAINDHIESEIEALAPTIDLSQGKPVLLSGHSGTIDVSGEAWIHYDQDH
LYLTAKIKDNVHAAAASGAEIWNNDSIQFALSPGIPGESGGWYEYGISDSPHGPQVYRWT
AMEGLPAGLVHNADAAVTRDEGQKLTIYKLAIPWSELTPIQPKNGDVMSFSLLVNENDGK
GRRGWIEWGGGIGTEKRPSLFRSMQWICP

Enzyme Prediction     

No EC number prediction in MGYG000001542_02066.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CBM9	943	1091	8.6e-19	0.7802197802197802
GH39	354	652	1.3e-17	0.7053364269141531

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd09621	CBM9_like_5	1.42e-43	927	1083	1	165	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other functional domains such as glycosyl hydrolases. The CBM9 module in these architectures may be involved in binding to carbohydrates.
cd09619	CBM9_like_4	3.20e-14	926	1083	15	166	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other domains.
cd00241	DOMON_like	2.85e-13	940	1083	10	153	Domon-like ligand-binding domains. DOMON-like domains can be found in all three kindgoms of life and are a diverse group of ligand binding domains that have been shown to interact with sugars and hemes. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.
pfam06452	CBM9_1	4.31e-07	943	1083	26	156	Carbohydrate family 9 binding domain-like. CBM9_1 is a C-terminal domain on bacterial xylanase proteins, and it is tandemly repeated in a number of family-members. The CBM9 module binds to amorphous and crystalline cellulose and a range of soluble di- and monosaccharides as well as to cello- and xylo- oligomers of different degrees of polymerization. Comparison of the glucose and cellobiose complexes during crystallisation reveals surprising differences in binding of these two substrates by CBM9-2. Cellobiose was found to bind in a distinct orientation from glucose, while still maintaining optimal stacking and electrostatic interactions with the reducing end sugar.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMF73229.1	0.0	11	1107	255	1353
QTH43804.1	0.0	2	1109	5	1116
QNK56522.1	0.0	213	1107	593	1481
AZS14129.1	1.87e-294	45	1107	215	1264
AZS16815.1	6.08e-294	212	1107	301	1183

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5JVK_A	5.88e-25	259	705	52	496	Structuralinsights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. [Bacteroides cellulosilyticus],5JVK_B Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. [Bacteroides cellulosilyticus],5JVK_C Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. [Bacteroides cellulosilyticus]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000250	0.999061	0.000199	0.000172	0.000151	0.000141

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001542_02066.