logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001546_00624

You are here: Home > Sequence: MGYG000001546_00624

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes provencensis
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes provencensis
CAZyme ID MGYG000001546_00624
CAZy Family GH2
CAZyme Description Exo-beta-D-glucosaminidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
845 MGYG000001546_5|CGC10 97537.65 6.0258
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001546 3805103 Isolate not provided not provided
Gene Location Start: 753534;  End: 756071  Strand: +

Full Sequence      Download help

MYLCTVLAAA  AAPVRQHLHD  DWQFRQARLN  NRYPASVPGT  IHTDLMANRI  IEDPYFRLNE60
RGVQWVDKED  WIYETQFEVD  GDLLARERIE  LVFEGLDTYA  DVCLNDEKIL  TTDNMFRRWR120
TEVKQLLHPG  KNTLKVYFHS  PIKIDLPKYD  SLPYRYEAIN  DQSANGGLFD  KRVSIFARKA180
GYHYGWDWGP  RLVTSGIWRP  VYLEGWDGAR  ISDVFYRQQE  VTAKRARIDV  EVEIAAARDL240
TEAVVTVTAP  GEGIEASVTT  PLRTGINKVT  VPLDIASPKL  WWTHELGEPH  LYEFRASFSA300
AGAADSRTTR  IGLRSLRLVR  DKVEDGTTFY  FELNGEPLFA  KGANYIPCDV  FLPRVTRAVY360
EKTIDDAAAV  NMNMLRVWGG  GVYEDDIFYE  LCDERGILVW  QDFMFACSIY  PAEGAWLENV420
RLEAEDNIRR  LRNHPSIAVW  CGNNECNDAW  FGWGWNTRYA  KQGHPEYDRI  IDTQFKRQYY480
EVLPEAVAAF  SPGTPYHPSS  PWSCYEGTSE  NNEGDTHFWN  VWHSRAPIAD  YNTTRSRFFS540
EYGFQSFPEY  ASVLRFAPEE  RDWDIESEVM  MAHQRGGSFA  NMRIRQYLED  EYWPARDFRT600
FLYMSHVLQG  DAIKTAIEAH  RRDKPYCWGS  LFWQHNDCWP  VASWASRDWY  GRWKAQHYFA660
RPAFDDILVS  PLAGENTLNV  RLVSDRRKTV  RGKLRITVMN  MDGAVLSKST  RSVTVAPNAS720
RNVYSADISG  LLRGCARNRA  IVVTEFTADD  RRYANIGYFV  PQKELALPEA  NIRWSAEPTT780
DGYAITLASD  RFVRAAWLSL  DGNEHFEDNY  FDLIPGVSRT  VRVATALSRS  EFDRMLQILH840
LQQTR845

Enzyme Prediction      help

EC 3.2.1.25

CAZyme Signature Domains help

Created with Snap428412616921125329533838042246450754959163367671876080214773GH2
Family Start End Evalue family coverage
GH2 14 773 9.7e-110 0.7473404255319149

CDD Domains      download full data without filtering help

Created with Snap428412616921125329533838042246450754959163367671876080213836LacZ676764Mannosidase_ig769841Ig_mannosidase209314Glyco_hydro_2194469ebgA
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 3.25e-112 13 836 10 802
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam17786 Mannosidase_ig 4.00e-19 676 764 1 91
Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
pfam17753 Ig_mannosidase 2.07e-14 769 841 1 76
Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.
pfam00703 Glyco_hydro_2 4.05e-14 209 314 1 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10340 ebgA 1.63e-08 194 469 194 478
cryptic beta-D-galactosidase subunit alpha; Reviewed

CAZyme Hits      help

Created with Snap42841261692112532953383804224645075495916336767187608027845CBK63191.1|GH23841QDO68488.1|GH23841ALJ60279.1|GH23841QUT88714.1|GH23841QUT74423.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
CBK63191.1 0.0 7 845 3 841
QDO68488.1 0.0 3 841 19 861
ALJ60279.1 0.0 3 841 19 861
QUT88714.1 0.0 3 841 19 861
QUT74423.1 0.0 3 841 19 860

PDB Hits      download full data without filtering help

Created with Snap4284126169211253295338380422464507549591633676718760802188442VJX_A188442JE8_A188447OP6_A188442WBK_A188442VQU_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2VJX_A 1.60e-221 18 844 11 837
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A 1.71e-221 18 844 13 839
Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A 1.76e-221 18 844 13 839
ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A 4.68e-221 18 844 11 837
Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
2VQU_A 2.04e-219 18 844 11 837
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQU_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron]

Swiss-Prot Hits      download full data without filtering help

Created with Snap428412616921125329533838042246450754959163367671876080218826sp|I2C092|MANBB_THETO16831sp|Q5B7W2|MANBB_EMENI37823sp|A2QYN2|MANBB_ASPNC11823sp|Q0CCA0|MANBB_ASPTN18823sp|Q4WAH4|MANBB_ASPFU
Hit ID E-Value Query Start Query End Hit Start Hit End Description
I2C092 3.73e-126 18 826 9 841
Beta-mannosidase B OS=Thermothelomyces thermophilus OX=78579 GN=man9 PE=1 SV=1
Q5B7W2 8.52e-124 16 831 6 833
Beta-mannosidase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=mndB PE=1 SV=2
A2QYN2 9.73e-122 37 823 32 828
Beta-mannosidase B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=mndB PE=3 SV=1
Q0CCA0 1.86e-121 11 823 2 826
Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2
Q4WAH4 1.05e-120 18 823 9 828
Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000031 0.000019 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001546_00624.