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CAZyme Information: MGYG000001546_01973

You are here: Home > Sequence: MGYG000001546_01973

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes provencensis
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes provencensis
CAZyme ID MGYG000001546_01973
CAZy Family GH116
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
543 61792.23 5.5827
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001546 3805103 Isolate not provided not provided
Gene Location Start: 2518656;  End: 2520287  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001546_01973.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH116 172 477 6.3e-50 0.7465564738292011

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04685 DUF608 5.41e-54 99 477 5 362
Glycosyl-hydrolase family 116, catalytic region. This represents a family of archaeal, bacterial and eukaryotic glycosyl hydrolases, that belong to superfamily GH116. The primary catabolic pathway for glucosylceramide is catalysis by the lysosomal enzyme glucocerebrosidase. In higher eukaryotes, glucosylceramide is the precursor of glycosphingolipids, a complex group of ubiquitous membrane lipids. Mutations in the human protein cause motor-neurone defects in hereditary spastic paraplegia. The catalytic nucleophile, identified in UniProtKB:Q97YG8_SULSO, is a glutamine-335, with the likely acid/base at Asp-442 and the aspartates at Asp-406 and Asp-458 residues also playing a role in the catalysis of glucosides and xylosides that are beta-bound to hydrophobic groups. The family is defined as GH116, which presently includes enzymes with beta-glucosidase, EC:3.2.1.21, beta-xylosidase, EC:3.2.1.37, and glucocerebrosidase EC:3.2.1.45 activity.
COG4354 COG4354 6.59e-15 26 485 266 721
Uncharacterized protein, contains GBA2_N and DUF608 domains [Function unknown].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUT37400.1 1.70e-270 1 534 300 835
QBJ18460.1 9.73e-270 1 534 300 835
QDO68263.1 1.95e-269 1 534 299 834
QUT66521.1 9.73e-269 1 534 1 544
QUT60790.1 2.58e-267 1 534 298 839

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      help

has no Swissprot hit.

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000077 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001546_01973.