CAZyme Information: MGYG000001560_00819

Basic Information

• Species: Massilioclostridium coli
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Massilioclostridium; Massilioclostridium coli
• CAZyme ID: MGYG000001560_00819
• CAZy Family: GH106
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1501	MGYG000001560_1|CGC11	168059.44	4.2499

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001560	2985330	Isolate	not provided	not provided

• Gene Location: Start: 988099; End: 992604 Strand: +

Full Sequence      

MKRRRLLSLGLVLAMSTSILIGNFSTATAEGASSDFYNQLVNHYTTPDIENRTEVRWWMA
EGAHTDETLEEEVQAIYDAGFRGIELCQLDNGNINAGDYGYGSDQWNHDFHLVMNKALDL
GMTLGLTSGTNWNTTNVPGLDPDSQAANQCVFQLNEQLTAGTSRTGAMPTNGDLREKATF
IGAYAYKKTGNNPITQDYRVIQTRENSSNPNTFTIETDVILDKQNTGLCFGAKDKNNFLM
WQINTLDGGNGKVLLRPHVCKNGQWVDTKNLDITKAIGYNASEIFGKKIHMKIEVKDGKT
IDTYFNGSDTSAVTYNIPTDKTGDFTLGKLMFRHNIKYANGTEELGRYDNIIVKDAAGTV
IFKEDFEDPSDTGFDGGEVVDGMFQAGLKQVEGEVNSAIELDSNNIIDVTDQVVLNEDNR
TGTLDWTAPDNGDYILMYYWQQGTAQESKPATKPSYCINYFDQEGVNATKEYWMEHVLND
PALNEKIKQGDVQLFMDSLEYTTGKGFANWSDDFAEEFKARKGYDITPYLILGVGLPQPK
GIDWHPEVYGTYNLDDANLGQRILNDFHDVQTELYMENLLIPLRDWLHEYGIKLRAQISY
GKYLEISEPSMAVDYPETERYNQANQLDMYRLWSGGAHLENKILSSETGAHVDYSYAYDY
QTLMQEAYVQFAAGVSRMNWHVWTSQWAPKSVGVNWPGFQSISSLPVFGLREPGYSEYKE
FNDHLGRVQQLLREGKSRTDIGMVHMKYGELILAPSVSGKQKHQNWLLRHEVMPGYFQST
ELQDHGYTYDYFSPEFFNSEDVYFDTETQTLELAGYKALVLYENWLTLDGAQAILDYAKQ
GLKVVIQDNAAVQTPYNDGNDEQLKAIIEELKTLPTVKSVASADDVYEALQELGVDPYSE
FAEENYQLLTQVRQDGDNMYLYAYNYCNDKYCGENHTTGMGHGLNAQTEIKMDGTFIPYY
IDAWSGEVTEVSNYRYEDGKTVFPISLDYGDVALYAFEPVEQEKLHVVSTDADKTYTMND
KIVVRATESGDSTTKLSNGTEVKYTFDVPQPYDITNWNLTVESWTPGEEIFRTEEVLGLA
TTEHTMDTVKTNTNVTLDQLTTWDQIPEIGKSVSGKGYYSATFHWDGNANGAYLDFGNLV
QSMQLTINGKKTADVNMNNPVIDISDYLVKGENTIEMEYSSNLTNVQLDRGAIKEKEKTQ
NMEGYSVKYRSYGPTQARIIPYVEQTIEVTSPTEVNKNILNSVITYAEQAKANGEYDNAI
ESVQKSFDKALADAKTIAENSASTQAEVDEAWQTLLNEIHKLGFIAGDKTELASLIAAAE
EINRELDRYMESGKAEFIAVLETAQTVYKNGDAMQEEINGVADDLLNAMLNLRFKADKSI
LEEVIAEANKIDASAYTTESYVVLTTAINEAKTVLENENASQEEVDAAVTNVQSAMDGLM
VVEGTENETLTTDNNTIQTGQENTTTKANAAKTGDFAPIAGIAVLAVAGITLFICRKNNN
F

Enzyme Prediction     

No EC number prediction in MGYG000001560_00819.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH106	402	1196	7.8e-73	0.8495145631067961

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam17132	Glyco_hydro_106	1.15e-24	45	917	2	829	alpha-L-rhamnosidase.
pfam07554	FIVAR	1.32e-06	1381	1439	3	68	FIVAR domain. This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Bacillus sp. Gellan lyase, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.
pfam07554	FIVAR	0.001	1240	1302	3	68	FIVAR domain. This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Bacillus sp. Gellan lyase, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.
COG1196	Smc	0.004	1186	1436	639	879	Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QGH71057.1	1.36e-270	29	1225	74	1129
AHF25191.1	9.16e-253	3	1227	17	1152
QGH70002.1	1.73e-125	14	1232	57	1120
QYN20448.1	2.58e-113	10	1185	21	1081
SDG73971.1	5.03e-113	38	1191	4	936

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MQM_A	2.01e-09	506	743	463	686	Glycosidehydrolase BT_0986 [Bacteroides thetaiotaomicron],5MQN_A Glycoside hydrolase BT_0986 [Bacteroides thetaiotaomicron]
5MWK_A	2.01e-09	506	743	463	686	Glycosidehydrolase BT_0986 [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P26831	3.50e-06	1233	1445	1339	1577	Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
E8MGH9	8.06e-06	1232	1500	1663	1935	Beta-L-arabinobiosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA2 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000897	0.997838	0.000300	0.000497	0.000257	0.000212

TMHMM  Annotations     

start	end
7	29
1476	1495