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CAZyme Information: MGYG000001571_00448
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Lacrimispora sp000526575 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lacrimispora; Lacrimispora sp000526575 | |||||||||||
| CAZyme ID | MGYG000001571_00448 | |||||||||||
| CAZy Family | GH5 | |||||||||||
| CAZyme Description | Endoglucanase A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 72465; End: 73877 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH5 | 33 | 304 | 2e-87 | 0.9927536231884058 |
| CBM65 | 352 | 462 | 5.2e-20 | 0.9385964912280702 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00150 | Cellulase | 1.45e-55 | 28 | 304 | 10 | 269 | Cellulase (glycosyl hydrolase family 5). |
| COG2730 | BglC | 7.99e-40 | 13 | 323 | 46 | 380 | Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism]. |
| pfam18259 | CBM65_1 | 2.80e-18 | 353 | 463 | 1 | 111 | Carbohydrate binding module 65 domain 1. This domain is found in the non-catalytic carbohydrate binding module 65B (CMB65B) present in Eubacterium cellulosolvens. CBMs are present in plant cell wall degrading enzymes and are responsible for targeting, which enhances catalysis. CBM65s display higher affinity for oligosaccharides, such as cellohexaose, and particularly polysaccharides than cellotetraose, which fully occupies the core component of the substrate binding cleft. The concave surface presented by beta-sheet 2 comprises the beta-glucan binding site in CBM65s. C6 of all the backbone glucose moieties makes extensive hydrophobic interactions with the surface tryptophans of CBM65s. Three out of the four surface Trp are highly conserved. The conserved metal ion site typical of CBMs is absent in this CBM65 family. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AEI34646.1 | 1.41e-119 | 4 | 446 | 379 | 816 |
| AWV80935.1 | 1.41e-119 | 4 | 446 | 379 | 816 |
| AAK81397.1 | 1.41e-119 | 4 | 446 | 379 | 816 |
| ADZ22510.1 | 1.41e-119 | 4 | 446 | 379 | 816 |
| CUH91691.1 | 2.23e-117 | 4 | 462 | 346 | 805 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6UI3_A | 6.75e-108 | 4 | 332 | 9 | 335 | GH5-4broad specificity endoglucanase from Clostridum cellulovorans [Clostridium cellulovorans] |
| 6PZ7_A | 1.11e-87 | 9 | 334 | 7 | 335 | GH5-4broad specificity endoglucanase from Clostridium acetobutylicum [Clostridium acetobutylicum ATCC 824] |
| 6GL2_A | 1.32e-86 | 6 | 333 | 9 | 336 | Structureof ZgEngAGH5_4 wild type at 1.2 Angstrom resolution [Zobellia galactanivorans] |
| 6GL0_A | 4.35e-86 | 4 | 333 | 1 | 330 | Structureof ZgEngAGH5_4 in complex with a cellotriose [Zobellia galactanivorans],6GL0_B Structure of ZgEngAGH5_4 in complex with a cellotriose [Zobellia galactanivorans],6GL0_C Structure of ZgEngAGH5_4 in complex with a cellotriose [Zobellia galactanivorans] |
| 6Q1I_A | 2.74e-85 | 10 | 338 | 13 | 355 | GH5-4broad specificity endoglucanase from Clostrdium longisporum [Clostridium longisporum],6Q1I_B GH5-4 broad specificity endoglucanase from Clostrdium longisporum [Clostridium longisporum] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P54937 | 1.82e-83 | 10 | 338 | 38 | 380 | Endoglucanase A OS=Clostridium longisporum OX=1523 GN=celA PE=1 SV=1 |
| P23660 | 5.79e-83 | 5 | 333 | 21 | 360 | Endoglucanase A OS=Ruminococcus albus OX=1264 GN=celA PE=1 SV=1 |
| P28623 | 7.25e-78 | 4 | 323 | 36 | 359 | Endoglucanase D OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engD PE=1 SV=2 |
| P28621 | 7.72e-78 | 4 | 333 | 35 | 371 | Endoglucanase B OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engB PE=3 SV=1 |
| P23661 | 4.27e-75 | 3 | 330 | 63 | 394 | Endoglucanase B OS=Ruminococcus albus OX=1264 GN=celB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000066 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |