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CAZyme Information: MGYG000001588_01800

You are here: Home > Sequence: MGYG000001588_01800

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Coriobacteriaceae; Collinsella;
CAZyme ID MGYG000001588_01800
CAZy Family GH84
CAZyme Description Hyaluronoglucosaminidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1830 193634.22 4.5981
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001588 2411406 MAG Canada North America
Gene Location Start: 300;  End: 5792  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.35 3.2.1.52

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH84 195 495 7.5e-91 0.9627118644067797

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam07555 NAGidase 7.59e-100 195 488 1 283
beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838 Glyco_hydro_20b 8.28e-18 36 188 2 123
Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
pfam00754 F5_F8_type_C 5.43e-06 1067 1223 10 127
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
NF033073 LPXTG_double 0.003 1795 1830 31 65
doubled motif LPXTG anchor domain. This unusual LPXTG-type C-terminal protein sorting domain occurs largely in the genus Clostridium and typically is separated from the main body of the protein by a glycine-rich linker sequence. In this domain, the classical sortase cleavage motif, LPXTG, has the consensus sequence VPLAxLPKTG. Much of this motif, the sequence VPLAxLP, is repeated an average 20 amino acids upstream within this domain. This unusual structure of a sortase recognition site-containing domain suggest a specialized form of interaction with its cognate sortase.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QWT17802.1 0.0 36 1566 38 1705
AXM91157.1 2.07e-316 36 1735 39 1735
VEG17470.1 8.01e-316 36 1735 39 1735
BBA47544.1 8.01e-316 36 1735 39 1735
BAQ98716.1 8.01e-316 36 1735 39 1735

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6PV4_A 1.13e-153 33 650 29 640
Structureof CpGH84A [Clostridium perfringens ATCC 13124],6PV4_B Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_C Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_D Structure of CpGH84A [Clostridium perfringens ATCC 13124]
6PWI_A 2.53e-84 36 656 34 626
Structureof CpGH84D [Clostridium perfringens ATCC 13124],6PWI_B Structure of CpGH84D [Clostridium perfringens ATCC 13124]
6PV5_A 9.48e-48 38 598 42 576
Structureof CpGH84B [Clostridium perfringens ATCC 13124]
5MI4_A 4.02e-40 125 580 80 510
BtGH84mutant with covalent modification by MA3 [Bacteroides thetaiotaomicron VPI-5482],5MI5_A BtGH84 mutant with covalent modification by MA3 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],5MI6_A BtGH84 mutant with covalent modification by MA3 in complex with Thiamet G [Bacteroides thetaiotaomicron VPI-5482],5MI7_A BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482]
2J4G_A 8.53e-40 125 580 68 498
Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482],2J4G_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P26831 9.16e-225 33 1425 36 1410
Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
Q89ZI2 5.64e-39 125 580 90 520
O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q8XL08 4.27e-37 40 566 48 542
O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Q0TR53 9.75e-37 40 566 48 542
O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
O60502 5.45e-19 196 447 63 314
Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000707 0.823116 0.175352 0.000296 0.000273 0.000238

TMHMM  Annotations      download full data without filtering help

start end
7 29
1803 1825