You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001589_00121
You are here: Home > Sequence: MGYG000001589_00121
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Pyramidobacter piscolens | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Synergistota; Synergistia; Synergistales; Dethiosulfovibrionaceae; Pyramidobacter; Pyramidobacter piscolens | |||||||||||
| CAZyme ID | MGYG000001589_00121 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Membrane-bound lytic murein transglycosylase C | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 123179; End: 125230 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 525 | 652 | 2.1e-28 | 0.8222222222222222 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd13401 | Slt70-like | 3.05e-65 | 508 | 654 | 2 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd16896 | LT_Slt70-like | 2.58e-44 | 509 | 650 | 1 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd00254 | LT-like | 5.79e-32 | 527 | 649 | 1 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| pfam01464 | SLT | 7.42e-28 | 520 | 622 | 5 | 108 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
| cd16893 | LT_MltC_MltE | 1.46e-25 | 514 | 645 | 1 | 158 | membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins. MltC and MltE are periplasmic, outer membrane attached lytic transglycosylases (LTs), which cleave beta-1,4-glycosidic bonds joining N-acetylmuramic acid and N-acetylglucosamine in the cell wall peptidoglycan, yielding 1,6-anhydromuropeptides. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QVL36679.1 | 3.06e-128 | 30 | 657 | 21 | 645 |
| ADE56509.1 | 1.28e-118 | 35 | 655 | 36 | 655 |
| AFM21693.1 | 2.92e-116 | 27 | 657 | 23 | 652 |
| CBL28056.1 | 7.44e-100 | 35 | 656 | 36 | 665 |
| QTX32804.1 | 6.73e-77 | 334 | 657 | 1 | 323 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5O1J_A | 6.85e-25 | 331 | 656 | 242 | 564 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5MPQ_A | 1.19e-24 | 331 | 656 | 238 | 560 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 6FPN_B | 1.25e-24 | 331 | 656 | 248 | 570 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5O24_A | 1.27e-24 | 331 | 656 | 252 | 574 | Lytictransglycosylase in action [Neisseria meningitidis] |
| 5O29_A | 1.31e-24 | 331 | 656 | 258 | 580 | Lytictransglycosylase in action [Neisseria meningitidis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O64046 | 2.36e-18 | 508 | 648 | 1418 | 1541 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
| O31976 | 2.36e-18 | 508 | 648 | 1418 | 1541 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
| P0AGC3 | 4.71e-18 | 384 | 657 | 350 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| P0AGC4 | 4.71e-18 | 384 | 657 | 350 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
| O31608 | 9.86e-17 | 514 | 648 | 62 | 179 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000287 | 0.999020 | 0.000187 | 0.000180 | 0.000159 | 0.000149 |
