You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001591_01005
You are here: Home > Sequence: MGYG000001591_01005
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Parabacteroides timonensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides timonensis | |||||||||||
| CAZyme ID | MGYG000001591_01005 | |||||||||||
| CAZy Family | GH97 | |||||||||||
| CAZyme Description | Retaining alpha-galactosidase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 41373; End: 43295 Strand: - | |||||||||||
Full Sequence Download help
| MNKRFLVFTF LVAVGLGMCI SCTTGDYELA SPDKKLVMHI RQQDNGELTY AFSANQTPLI | 60 |
| NESSLGFKLE SEEVIPSSGW KIEHVSDRQV RGEWKPLWGK RAVVPDHYNE LTIELTRPLG | 120 |
| TPDRMELIAR VYNDGIAFQY RIPEGNAGEA NVLAEQTTYN FADDYTAWFY NGENHNIGPE | 180 |
| KLTETDGTRL PVMTVKAGDN HYMAIHEANL ETGAPLVLQS KGGERLFSVA SKPITLTSGY | 240 |
| TSAWRVILYG TTPGVLTDSH LIELLNPDPD PAYDFSWVKP GMAVWDWRIN GAEWEGFKYT | 300 |
| MSYPSWIRMV DFAAAQGFKY LVLDANWYGP EFESDSHPVE GDKAKDVQNL IAYGKEKGVG | 360 |
| IWLYLNDVGG RKYPIEQTLK QYGDWGAAGV KYGFMSGNQE EKNLWTRKIT ELCAKNHLLV | 420 |
| DYHDGPVHPY GQMRTWPNAV TREYCHAQLD AHRVFEPKTF VTTVFVNMVA GPVDMNNGMF | 480 |
| DLRQGHTTRV DESQPVPSTL VSEAARTLIA FSGVTILPDI PEYYEKYPAL LDFLSSQKMP | 540 |
| WKESRTLAGE IGEYIVMMRQ TEEAYLVGAA TNESGRTIDL PLTFLEDGTF NAEVVEDGDD | 600 |
| AHYLTNRETL KVSKKQVTNK DVLKLKLAPG GGACLKFIKQ | 640 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH97 | 19 | 637 | 3.4e-149 | 0.9889064976228209 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam14508 | GH97_N | 7.10e-56 | 31 | 267 | 1 | 234 | Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole. |
| pfam10566 | Glyco_hydro_97 | 1.45e-49 | 274 | 536 | 1 | 276 | Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands. |
| pfam14509 | GH97_C | 1.56e-33 | 541 | 638 | 1 | 97 | Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUT75478.1 | 0.0 | 1 | 640 | 1 | 641 |
| QDO68310.1 | 1.59e-317 | 31 | 640 | 26 | 632 |
| BBE16916.1 | 2.13e-297 | 29 | 635 | 28 | 634 |
| ABQ06816.1 | 6.55e-263 | 29 | 640 | 32 | 614 |
| QUT49475.1 | 7.48e-258 | 256 | 635 | 1 | 380 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5HQ4_A | 8.75e-57 | 31 | 637 | 5 | 658 | AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQB_A | 8.75e-57 | 31 | 637 | 5 | 658 | AGlycoside Hydrolase Family 97 enzyme (E480Q) in complex with Panose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQC_A | 8.75e-57 | 31 | 637 | 5 | 658 | AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5E1Q_A | 1.34e-56 | 31 | 636 | 20 | 653 | Mutant(D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482],5E1Q_B Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482] |
| 3A24_A | 1.01e-55 | 31 | 636 | 6 | 639 | Crystalstructure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron],3A24_B Crystal structure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8A6L0 | 2.41e-57 | 18 | 636 | 9 | 660 | Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1 |
| D7CFN7 | 1.84e-50 | 46 | 600 | 57 | 591 | Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1 |
| G8JZS4 | 1.25e-45 | 18 | 632 | 13 | 718 | Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000019 | 0.000020 | 1.000024 | 0.000000 | 0.000000 | 0.000000 |
