CAZyme Information: MGYG000001591_01715

Basic Information

• Species: Parabacteroides timonensis
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides timonensis
• CAZyme ID: MGYG000001591_01715
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
936	MGYG000001591_22|CGC1	106681.13	5.9894

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001591	5999279	MAG	China	Asia

• Gene Location: Start: 44037; End: 46847 Strand: +

Full Sequence      

MKKIIVLALLTLLFEGCITAQKNNIDLSGEWMIKLDPEDKGLSEQWFNNEFNDRITLPGS
LQEQGYGYDIDIHTRWTGQIVDSTWYNAPEYEKYRQKEDLKAPFWLNPEKHYVGVAWYRK
DVDIPSSWKGKTLLLELERTHWETNLFVDGKEIGHQDGISTPHRYELTGLEPGKHNIVLR
IDNRVHIPVGINSHSVSDHTQSNWNGVIGKLMLSVKPQVSIEDVQIYPDLVAKKVTVNVS
VKGLGKARLSFQIVTPDGEPVGTPTRLEQNVSNGVMSLEAVVNAGNNIRLWSEHTPDFYR
LKTTVTSSGESDERYTNFGFREFKKVGTRFHVNGQPTFLRGTLECCIFPLTGYPSTDAKY
WEKIYRSCREFGLNHIRFHSWCPPEIAFHVADSMGLYLQVECGAWSNVGEGGYIDEWLYA
EGERILKEHGNHPSFCMMAHGNEPGGANRDQYLSRLVEYWKKKDNRRVYTSGAGWPYIEN
ADYWNAVEPRIQRWGKGLNSIINAQPPCSDYDFREMIKKDMPTVSHEIGQWCVYPNFKEI
GKYTGVLKAKNFEIFKETLEENNMGHLADDFLYASGKLQVLCYKADIEAALRTPGFGGFQ
LLDLHDFPGQGTALVGVLDAFWDKKGYVDGKTYSMFCSETVPLVRFPKMVWMNNEQMNVP
VEFAHFGEKPLQNAPIFWTAVNADNEIVGKGRFSKDLPLDNCIPVGNIDLSFEQLKEPTQ
LTITVGIENTEIKNQWNIWVYPVQKAMVNNQPYISSKFDNTVIEKLNKGESVFVISPRGS
VLPEKGGDIAIGFSSIFWNTAWTRNQAPNTLGILCDPSHPALSAFPNEGYSDYQWWDIVS
DCDAMIMDDFPVGFKPIVYLIDDWFKNRKLGILFEAKVGTGKLVVCSSDLNRNPEKYPAA
AQFKQSILEYMASDKFDPRNELKPEVIKSLFVREKK

Enzyme Prediction     

No EC number prediction in MGYG000001591_01715.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	20	492	2.3e-70	0.5079787234042553

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	9.43e-30	25	474	13	434	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	2.08e-21	19	341	7	296	beta-D-glucuronidase; Provisional
PRK10340	ebgA	1.87e-16	27	467	44	470	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703	Glyco_hydro_2	2.77e-12	219	321	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam02837	Glyco_hydro_2_N	1.08e-09	27	217	4	169	Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT75482.1	0.0	27	931	26	932
QRO25183.1	0.0	23	935	24	935
SCD20884.1	0.0	2	925	3	935
QCW99525.1	0.0	13	931	14	940
SDS50045.1	0.0	2	930	8	944

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6D8K_A	5.09e-17	2	471	5	442	Bacteroidesmultiple species beta-glucuronidase [Bacteroides ovatus],6D8K_B Bacteroides multiple species beta-glucuronidase [Bacteroides ovatus],6D8K_C Bacteroides multiple species beta-glucuronidase [Bacteroides ovatus],6D8K_D Bacteroides multiple species beta-glucuronidase [Bacteroides ovatus]
3GM8_A	5.41e-17	74	472	32	424	ChainA, Glycoside hydrolase family 2, candidate beta-glycosidase [Phocaeicola vulgatus ATCC 8482]
6D8G_A	8.39e-13	74	470	60	469	D341AD367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii],6D8G_B D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii]
6LEM_B	1.44e-12	27	470	13	440	ChainB, Beta-D-glucuronidase [Escherichia coli]
5UJ6_A	1.44e-12	74	470	52	461	CrystalStructure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],5UJ6_B Crystal Structure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],6NZG_A Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis],6NZG_B Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P05804	7.94e-12	27	470	15	442	Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000215	0.262017	0.737436	0.000110	0.000119	0.000101

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001591_01715.