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CAZyme Information: MGYG000001599_00043

You are here: Home > Sequence: MGYG000001599_00043

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phocaeicola sp900544075
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900544075
CAZyme ID MGYG000001599_00043
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
765 MGYG000001599_1|CGC3 86284.1 5.0891
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001599 4213385 MAG China Asia
Gene Location Start: 78180;  End: 80477  Strand: +

Full Sequence      Download help

MKKLFFCLLG  GAMMLNSCTD  DSGIFVPDGI  KEPTLPVETK  PNEVVKGDVF  SKLNLDYPGL60
EKVKQHYEAG  EHYLAAKELL  EYYRWRSNVV  NPAVPAFVTA  SAVDINKANQ  ALDYRFVVAK120
FVETKGDTDD  KDIYYSFKNN  DGTINWGFKP  DVQGVDREFY  YQQHRHQWME  PQAKAYAYTK180
NEAYFNNWVD  VYTSWMAKYP  CPNAPFDDPK  IYNLEPGYEW  KALQPAERVL  SQLNVIPCYL240
NSPNFTPEWL  TTVLNAFAEN  VEMIRMNYIS  EGNIRATQGQ  AVVSAGILMP  EFKNAEQWVT300
EGLQTMNMDE  QFLFDGVHVD  LDLSYHIAAI  SDYLEVYNLA  KANNRLDILP  SGYIEKLTNA360
VSFVKDMIYP  NYTIDNFNDT  RSSSYAKSTL  MNRLKDYLAV  FPEDEELKWM  AWEGAKGGTK420
PTWKSKAYDV  AGYYMLRTAN  WGANDGMMVI  HKNNDNSVKE  WHCQPDNGTF  SFWYKGRNFL480
PDAGVYSYDD  PDATGMRGKY  RQYVLHNTMS  IYTKNIFFNE  NGKPTEKTTT  GKMLKHESGS540
NYELIVTENT  PYMAGPLNSD  NTNVMNGDFK  HRRAIYMVDN  KFVVLVDEGY  SSSVADGGKK600
VNLNFHLYSE  AGEEPKKIED  LSKPECNVNG  IDAPVKSSDG  MSAYAKTKLS  GSNLLIKSFV660
ETKSGFDMGL  GKKADELPIS  DNTGTMVGKK  RDWLQVHLNI  PKNLENVAAR  LITVLYPSDG720
TAGDGSNISA  EFTDNVGATA  GTFHPDGAAI  KVTVDGQTYE  LKYTL765

Enzyme Prediction      help

EC 4.2.2.8

CAZyme Signature Domains help

Created with Snap3876114153191229267306344382420459497535573612650688726431588PL12
Family Start End Evalue family coverage
PL12 431 588 1.1e-37 0.9923664122137404

CDD Domains      download full data without filtering help

Created with Snap387611415319122926730634438242045949753557361265068872650409Hepar_II_III_N421607Hepar_II_III
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 1.40e-130 50 409 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 5.17e-15 421 607 2 164
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Created with Snap38761141531912292673063443824204594975355736126506887261761QRM98068.1|PL12_21761CBK68728.1|PL12_21761QUT82727.1|PL12_21761QDM12096.1|PL12_21761QNL36915.1|PL12_2
Hit ID E-Value Query Start Query End Hit Start Hit End
QRM98068.1 2.89e-202 1 761 1 737
CBK68728.1 2.89e-202 1 761 1 737
QUT82727.1 2.24e-201 1 761 1 736
QDM12096.1 2.24e-201 1 761 1 736
QNL36915.1 2.24e-201 1 761 1 736

PDB Hits      download full data without filtering help

Created with Snap387611415319122926730634438242045949753557361265068872617654FNV_A427655JMD_A427655JMF_A507074MMI_A506994MMH_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNV_A 2.09e-128 1 765 1 702
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]
5JMD_A 2.22e-90 42 765 11 655
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A 9.90e-81 42 765 11 655
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4MMI_A 2.49e-69 50 707 10 634
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
4MMH_A 6.59e-69 50 699 10 626
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap38761141531912292673063443824204594975355736126506887261765sp|Q89YR9|HEPC_BACTN45765sp|C7EXL6|HEPC_BACSE50699sp|Q59289|HEPC_PEDHD
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q89YR9 1.14e-127 1 765 1 702
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1
C7EXL6 8.77e-87 45 765 25 666
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q59289 4.94e-68 50 699 34 650
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000000 0.000000 1.000057 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001599_00043.