logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001601_01193

You are here: Home > Sequence: MGYG000001601_01193

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Peptostreptococcus russellii_A
Lineage Bacteria; Firmicutes_A; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Peptostreptococcus; Peptostreptococcus russellii_A
CAZyme ID MGYG000001601_01193
CAZy Family GH25
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
511 MGYG000001601_16|CGC1 58465.02 7.9886
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001601 1998441 MAG China Asia
Gene Location Start: 44015;  End: 45550  Strand: +

Full Sequence      Download help

MSLKGVDISK  YNGNCDFKKA  KDSGIDFVII  KAGSGASGKD  PFWDKNYNYA  KAAGLGVGAY60
WYCYATSVEQ  AKREAREFVG  LLKDKKLDYP  AYLDLEDNKY  QGCLGNKLRT  DIAEAFCEVV120
QNAGYYTGIY  SMMSWFNSKF  DMSRLKKYDL  WIARWRDINL  GVGYSGLGQV  GMWQYSNQGR180
VSGIGNTGEG  GVDVNIAYLN  YPSIISGGIS  NIATEDIIES  SNTVSNEAQK  MINKMNAWLG240
KSEANRQHKD  IIDIYNNHRP  LPRGYKVKYT  DEWCATTISA  AAIQCGLVDK  IGKECSVQRF300
IDIFKQKGIW  IEDGCITPIP  GDIICFNWDN  STQPNDGWAD  HIGLVEKVSN  GRITVIEGNN360
DESVKKREIP  IAWGYIRGYA  RPCYCGVSTN  EGWKKENNKW  VFYKNSKKVC  GWLKDKNKWY420
YIDPKTKEMI  TGWLKYNNNW  FYFNNNGSMR  TGWLEYNNKW  YYFNSNGYMH  IGWLEYNGHK480
FYFDDDGSMI  SDCSLILNGM  EYIFDSRGYM  Q511

Enzyme Prediction      help

No EC number prediction in MGYG000001601_01193.

CAZyme Signature Domains help

Created with Snap2551761021271531782042292552813063323573834084344594856184GH25
Family Start End Evalue family coverage
GH25 6 184 7.8e-49 0.9943502824858758

CDD Domains      download full data without filtering help

Created with Snap2551761021271531782042292552813063323573834084344594854198GH25_LytC-like4197GH25_muramidase4195GH25_Lyc-like6184Glyco_hydro_25392510PspC_subgroup_1
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd06414 GH25_LytC-like 1.74e-71 4 198 2 191
The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.
cd00599 GH25_muramidase 1.37e-40 4 197 1 186
Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.
cd06525 GH25_Lyc-like 5.94e-34 4 195 1 182
Lyc muramidase is an autolytic lysozyme (autolysin) from Clostridium acetobutylicum encoded by the lyc gene. Lyc has a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.
pfam01183 Glyco_hydro_25 1.82e-30 6 184 1 180
Glycosyl hydrolases family 25.
NF033838 PspC_subgroup_1 4.24e-28 392 510 487 604
pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

CAZyme Hits      help

Created with Snap2551761021271531782042292552813063323573834084344594851384BAK46682.1|GH254384AAW39696.1|CBM50|GH254389QJU22483.1|GH254391QJU22680.1|GH25222391QEI31358.1|CBM50|GH73
Hit ID E-Value Query Start Query End Hit Start Hit End
BAK46682.1 1.43e-105 1 384 1 387
AAW39696.1 1.18e-99 4 384 3 380
QJU22483.1 2.27e-86 4 389 5 371
QJU22680.1 2.14e-82 4 391 6 384
QEI31358.1 1.69e-64 222 391 153 322

PDB Hits      download full data without filtering help

Created with Snap25517610212715317820422925528130633235738340843445948521954KRU_A23664KRT_A31951JFX_A32002WAG_A61853HMC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4KRU_A 5.38e-18 2 195 19 205
X-raystructure of catalytic domain of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101]
4KRT_A 1.82e-17 2 366 19 352
X-raystructure of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101],4KRT_B X-ray structure of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101]
1JFX_A 3.81e-12 3 195 5 200
Crystalstructure of the bacterial lysozyme from Streptomyces coelicolor at 1.65 A resolution [Streptomyces coelicolor]
2WAG_A 3.31e-11 3 200 16 209
TheStructure of a family 25 Glycosyl hydrolase from Bacillus anthracis. [Bacillus anthracis str. Ames]
3HMC_A 3.62e-09 6 185 8 172
Endolysinfrom Bacillus anthracis [Bacillus anthracis]

Swiss-Prot Hits      download full data without filtering help

Created with Snap2551761021271531782042292552813063323573834084344594852195sp|P26836|LYS_CLOPE3189sp|P34020|LYS_CLOAB2196sp|Q8X7H0|YEGX_ECO572196sp|P76421|YEGX_ECOLI2196sp|Q8FFY2|YEGX_ECOL6
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P26836 1.11e-17 2 195 8 194
Probable autolytic lysozyme OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=lyc PE=3 SV=2
P34020 5.36e-12 3 189 1 176
Autolytic lysozyme OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) OX=272562 GN=lyc PE=1 SV=1
Q8X7H0 1.02e-11 2 196 66 253
Uncharacterized protein YegX OS=Escherichia coli O157:H7 OX=83334 GN=yegX PE=3 SV=2
P76421 1.37e-11 2 196 66 253
Uncharacterized protein YegX OS=Escherichia coli (strain K12) OX=83333 GN=yegX PE=3 SV=2
Q8FFY2 1.85e-11 2 196 66 253
Uncharacterized protein YegX OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=yegX PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999903 0.000114 0.000006 0.000001 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001601_01193.