CAZyme Information: MGYG000001615_04393

Basic Information

• Species: Eisenbergiella sp900548905
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella sp900548905
• CAZyme ID: MGYG000001615_04393
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1136	MGYG000001615_43|CGC2	129449.28	5.3317

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001615	6842156	MAG	China	Asia

• Gene Location: Start: 48283; End: 51693 Strand: +

Full Sequence      

MDFMIKRGQRYRVRVSEKETEAVKIAVSNLETDLAKVLGGTPAREKEADVPEILVGTLGC
SEEIGASIDSSRLQDEDGNLRKEAYIQCVRGGRLVIAGADRRGTIYGIYTFCEAIGVSPW
YFWADVPVKQKQEILLPEGYAKADYPSVEYRGIFINDEEELEAWVKKHMGETTIGVKTYE
KVFELLLRLKGNYIWPAMHVNSFNQKRENGALADRMGIVVGTSHCDMLMRSNNREWHPWI
ESKGCQDAVYDYSIPGRNREILKEYWRESVEQNRDFEVCYTLGMRGIHDSGFETKTLEGK
TEEEKRKAKTELLETIIRDQRGILSQTLGHDTMMTFIPYKEVLKLYDNGLEIPEDMTLVW
ANDNYGYIRRYPSEKEQHRRGGNGIYYHNSYWAPPGMSYVFLCSIPLAHTRNELKKAYAE
GIRKLWVLNSGSMKPLEQEMEFFLRLAWEIGREDALTADVDAYAADWIDRNFSGGHGRET
AALLNDFSQLTNVRKLENMDYDAFSQIAYGDEAAVRIHKYEELFHKGNAIYSRLPEPEKD
AFFQLVLMRIHAAYFTNCQFYYGDRSTLCVKQGKMQAARFYTRKSMEFDDARRKMLHYYN
KTMSGGKWDGILNPEGFPPPRAAMMPVCTPPLEIGERRMLVTVWNGADSLSFTKPGEKWI
EIGNAGEGEVEFSVCAPEWLSVSETSGRVGSEKRILLSPKGFDRDRQGEIVISDRTEGEE
VRIPVRVRALSADCPNTEDDGMISVEADTAESSAFRVIHRLGRCRGNLMEAAVDRQQWES
GRPDAAEALTYPFYLTRDTPAEGALLEIHRFPSLNSTGRIRIGVAVDDGPAAIVESFSND
EWRGNWKQNVLNNVDRLYRKLPEMKKGLHHLSFYPVDRYFAFTRFVIYQGERKENSLGLP
GGDQRLPELWDLNAWENQFYGDISLKPRPVEYAPAESGEDSLTVTSLVKYPDAYAEPITP
EWYLKAGKRGPEEVSGAIRIDAATALSGSSRAWTEGSGWEYCSSESFGRSGLAMYIRDRS
LCWETAEEAPSLHYRFRCAGGMYRIWMLAKFNLREEAGFAMGIDGELFSEEELYNGGNLF
RYEAEQIYRWVPAARMTIGPGGHVLQVRPLAAGLRIDRLYLTKGEELPPPDTAWKG

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	5	878	3.1e-190	0.9799139167862266

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	1.06e-139	144	497	1	333	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.69e-21	738	900	4	171	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	4.77e-04	15	109	25	118	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QOV19968.1	0.0	1	1134	2	1120
AIQ53763.1	0.0	13	1135	12	1201
QGH34463.1	0.0	9	1134	15	1218
AIQ48273.1	0.0	13	1135	12	1201
AIQ31286.1	0.0	4	1135	5	1202

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	1.39e-96	2	649	19	652	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4ZMH_A	8.09e-94	15	898	27	929	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
7PUG_A	2.47e-90	4	612	19	625	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	1.39e-87	4	612	18	624	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4C90_A	7.93e-80	4	612	46	640	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000038	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001615_04393.