CAZyme Information: MGYG000001619_02436

Basic Information

• Species: UBA9502 sp900540335
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA9502; UBA9502 sp900540335
• CAZyme ID: MGYG000001619_02436
• CAZy Family: GH2
• CAZyme Description: Beta-glucuronidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
606	MGYG000001619_51|CGC1	69243.88	5.1061

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001619	2970880	MAG	China	Asia

• Gene Location: Start: 15240; End: 17060 Strand: -

Full Sequence      

MLYPRENEVRAVMDLSGIWNFELGDAGEPGETCGSLKAPELISVPASYNDQKEDPAYRNH
YGWVYYERTVAVPASLKGQRLVLRFDAVTHAARVYINGKLAAEHKGGFLPFEVEITDLIP
AGTRGILTVAADNRIHHGTLPVGNEGAIAFFGSDNPGVPSVEAAKRWAKPQNIPNFDFFN
YAGINRPVRLYTTPEIYIDDITLVPSVEGADGLVEYAVSVKGGERENLISEMTVIEILDE
NRNCVARGTGDAGRLRIPQAKLWWPWPGTPYLYTARISCGEDVYEQMFGIRTVRVEGTKF
LINEKPFYFKGFGKHEDSAFHGRGLDLCLDVKDVGLIHWLHANSFRTSHYPYAEEMYELC
DREGIVVIDETPAVGIGAGEAQNPYETFPVREHHEQVLREMIARDKNHPSVVMWSMGNEP
DTEHFPQSAYEYWHTLYEYTHSLDPQNRPVTFVCCQNNYERDLVTRTMDVVCINRYYGWY
NLSGNLDAACYAWNQELDFWEKQGKPVMVTEYGADAIAGIHETVPEMFSEEYQMEFYRRQ
NAEFDKRSFFIGEHVWGFADFATVQGCMRADGNKKGLFTRDRRPKMAAHYFKKRWSEIPD
FDYKPF

Enzyme Prediction     

EC	3.2.1.31

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	7	596	3.3e-108	0.6156914893617021

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK10150	PRK10150	0.0	1	606	1	603	beta-D-glucuronidase; Provisional
COG3250	LacZ	1.77e-106	1	605	1	605	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam02836	Glyco_hydro_2_C	3.31e-83	293	598	1	300	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10340	ebgA	2.80e-36	66	560	113	547	cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525	lacZ	5.43e-25	66	450	124	485	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CUO31707.1	0.0	1	604	1	600
AEN95939.1	0.0	1	604	6	605
CBL08206.1	0.0	1	604	1	599
CBL12719.1	0.0	1	604	1	599
VCV23245.1	0.0	1	604	1	599

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6U7I_A	3.69e-291	1	604	1	597	Faecalibacteriumprausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_B Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_C Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_D Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii]
6LD0_A	1.23e-239	1	604	3	669	ChainA, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1]
5Z1B_A	1.50e-238	1	604	25	691	Structureof Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679],5Z1B_B Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679],5Z1B_C Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679],5Z1B_D Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679]
6D4O_A	9.94e-210	1	604	4	612	Eubacteriumeligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate [Lachnospira eligens]
6BO6_A	3.62e-209	1	604	1	609	Eubacteriumeligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate [[Eubacterium] eligens ATCC 27750]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P05804	2.26e-157	1	605	1	597	Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2
O97524	2.06e-153	1	598	27	628	Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1
O18835	2.06e-153	1	598	27	628	Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1
Q4FAT7	5.36e-151	1	598	28	629	Beta-glucuronidase OS=Sus scrofa OX=9823 GN=GUSB PE=3 SV=1
P06760	3.00e-149	1	598	27	625	Beta-glucuronidase OS=Rattus norvegicus OX=10116 GN=Gusb PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000041	0.000012	0.000001	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001619_02436.