CAZyme Information: MGYG000001622_00295

Basic Information

• Species: Enterocloster sp900549235
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Enterocloster; Enterocloster sp900549235
• CAZyme ID: MGYG000001622_00295
• CAZy Family: PL12
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
671	MGYG000001622_1|CGC2	77192.16	4.7719

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001622	3555335	MAG	China	Asia

• Gene Location: Start: 294381; End: 296396 Strand: +

Full Sequence      

METPMTKERLFSRGDQHFFMDDPAGIAAYCRQHWPEDCAHILRVADEVCRNYFLFDLEHD
LERTWEPVSFDPEGEVDWEYRPGNDPEFTFQFNRHRFFICLGQAYWLTGDERYARHFFRL
LMSWISGVKRTPETEQTTWRILEAGIRGENWVKAIRYFKDSPLMTDDIAAAFYDCLVEHA
EYIIKMHSPYRYISNWGVMENHGLFEIGIAMPDEELRSRYTSIALERLETEARLQILGDG
IQWEQSPMYHNEVLHCYEDVLILASRNEIPVPEAITRAVHRMACADLAWKKPDHKQFLMG
DSDDMDIRDYISIAAFLFHDPVLRSGGYPILDFESVWDLGLEAAGIYEGLESQEPDFVSC
ALTDSGNYLLRSGWGEKENLLHFHCGTMGAGHGHSDKLHVDLVIGGEDVLTDAGRYTYVV
DRGRFEFKDPPAHNTLTADGEYFTVCKDSWECDKLCQPVKQQYKFTDQYELVQGGHLGYA
YKGIFINRKVLYIRPDIYIIMDEMYAQGEHSYEQYWNFSERGELEEMPGGCTFTGDQAKA
RLVFLTPGVSVTLGESRIARHYNRCETRKRLCVQIRKEGFASLITVIKGGEGTFEASRIP
VRSALKGITYPEEMAEGVKIQAEGKTYVVIFCHQEVNSPTDLTEAEGCMGYGNVIVFEKG
KDEIGGTVMCW

Enzyme Prediction     

No EC number prediction in MGYG000001622_00295.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
PL12	365	502	5.8e-47	0.9925925925925926

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam16889	Hepar_II_III_N	2.14e-38	69	302	76	317	Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940	Hepar_II_III	6.46e-18	384	582	31	226	Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QQR04156.1	0.0	3	669	7	703
ANU50362.1	0.0	3	669	7	703
QIX90196.1	0.0	3	669	7	701
AEN95953.1	1.03e-257	5	671	1	674
SEU07992.1	1.31e-225	5	657	1	655

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4MMH_A	1.65e-30	36	520	58	520	Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4MMI_A	1.65e-30	36	520	58	520	Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
5JMD_A	7.08e-27	69	625	95	647	HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
4FNV_A	1.39e-25	45	631	104	700	CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A	8.81e-25	69	533	95	552	HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q59289	9.80e-30	36	520	82	544	Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
Q89YR9	7.62e-25	45	631	104	700	Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1
C7EXL6	8.78e-24	43	625	87	658	Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000084	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001622_00295.