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CAZyme Information: MGYG000001622_00606

You are here: Home > Sequence: MGYG000001622_00606

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Enterocloster sp900549235
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Enterocloster; Enterocloster sp900549235
CAZyme ID MGYG000001622_00606
CAZy Family PL21
CAZyme Description Heparin and heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
802 MGYG000001622_2|CGC2 89374.68 4.9325
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001622 3555335 MAG China Asia
Gene Location Start: 54350;  End: 56758  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001622_00606.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL21 434 494 6.8e-24 0.8888888888888888

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam18675 HepII_C 2.59e-10 716 799 1 86
Heparinase II C-terminal domain. Heparinase II (HepII) is an 85-kDa dimeric enzyme that depolymerizes both heparin and heparan sulfate glycosaminoglycans. The protein is composed of three domains: an N-terminal alpha-helical domain, a central two-layered beta-sheet domain, and a C-terminal domain forming a two-layered beta-sheet. The C-terminal domain contains nine beta-strands packed together in a manner resembling a beta-barrel.
pfam07940 Hepar_II_III 4.15e-04 434 490 29 85
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCI63941.1 1.19e-171 55 801 31 791
BCI63940.1 4.41e-164 37 795 20 787
BBH20141.1 1.00e-130 49 800 221 958
QHW00380.1 7.11e-128 63 802 70 801
ACN29695.1 1.32e-127 64 797 46 769

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2FUQ_A 1.88e-123 53 797 13 743
ChainA, heparinase II protein [Pedobacter heparinus],2FUQ_B Chain B, heparinase II protein [Pedobacter heparinus]
3E80_A 1.98e-123 53 797 15 745
Structureof Heparinase II complexed with heparan sulfate degradation disaccharide product [Pedobacter heparinus],3E80_B Structure of Heparinase II complexed with heparan sulfate degradation disaccharide product [Pedobacter heparinus],3E80_C Structure of Heparinase II complexed with heparan sulfate degradation disaccharide product [Pedobacter heparinus]
3E7J_A 1.23e-120 53 797 15 745
ChainA, Heparinase II protein [Pedobacter heparinus],3E7J_B Chain B, Heparinase II protein [Pedobacter heparinus]
2FUT_A 5.61e-117 53 797 14 744
ChainA, heparinase II protein [Pedobacter heparinus],2FUT_B Chain B, heparinase II protein [Pedobacter heparinus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C6XZB6 1.98e-122 53 797 38 768
Heparin and heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepB PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.004516 0.980108 0.013658 0.001006 0.000413 0.000268

TMHMM  Annotations      download full data without filtering help

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