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CAZyme Information: MGYG000001625_00279

You are here: Home > Sequence: MGYG000001625_00279

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eikenella corrodens
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Neisseriaceae; Eikenella; Eikenella corrodens
CAZyme ID MGYG000001625_00279
CAZy Family GT25
CAZyme Description Lipooligosaccharide biosynthesis protein lex-1
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
270 31661.56 8.5975
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001625 1812730 MAG China Asia
Gene Location Start: 8788;  End: 9600  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001625_00279.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT25 1 186 9.1e-36 0.994475138121547

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3306 COG3306 1.06e-48 1 256 2 248
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis].
pfam01755 Glyco_transf_25 8.95e-48 1 186 1 200
Glycosyltransferase family 25 (LPS biosynthesis protein). Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.
cd06532 Glyco_transf_25 3.89e-29 3 186 1 128
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.
cd22189 PGAP4-like_fungal 0.001 63 108 163 221
uncharacterized fungal proteins similar to Post-GPI attachment to proteins factor 4. This subfamily contains uncharacterized fungal proteins with similarity to animal post-GPI attachment to proteins factor 4 (PGAP4), also known as post-GPI attachment to proteins GalNAc transferase 4 or transmembrane protein 246 (TMEM246). PGAP4 has been shown to be a Golgi-resident GPI-GalNAc transferase. Many eukaryotic proteins are anchored to the cell surface through glycolipid glycosylphosphatidylinositol (GPI). GPIs have a conserved core but exhibit diverse N-acetylgalactosamine (GalNAc) modifications. PGAP4 knockout cells lose GPI-GalNAc structures. PGAP4 is most likely involved in the initial steps of GPI-GalNAc biosynthesis. In contrast to other Golgi glycotransferases, it contains three transmembrane domains. Proteins from this subfamily contain the putative catalytic site of PGAP4 and may have similar activities.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SNW07352.1 4.18e-196 1 270 1 270
VEJ21792.1 7.33e-69 1 265 1 270
QEH46616.1 1.06e-68 3 260 7 261
ACX81839.1 1.06e-68 3 260 7 261
QEH48730.1 1.06e-68 3 260 7 261

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q57394 9.13e-59 4 270 4 266
Lipooligosaccharide biosynthesis protein lic2B OS=Haemophilus influenzae OX=727 GN=lic2B PE=3 SV=1
Q03974 3.24e-56 2 261 4 282
Lipooligosaccharide biosynthesis protein lex-1 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=lex1 PE=1 SV=1
Q50950 4.91e-56 2 233 1 235
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtE OS=Neisseria gonorrhoeae OX=485 GN=lgtE PE=3 SV=1
Q51116 8.49e-56 2 227 1 229
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtB OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=lgtB PE=3 SV=2
Q50947 3.79e-55 2 227 1 229
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtB OS=Neisseria gonorrhoeae OX=485 GN=lgtB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001625_00279.