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CAZyme Information: MGYG000001631_01090
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bilophila sp900553145 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Desulfobacterota; Desulfovibrionia; Desulfovibrionales; Desulfovibrionaceae; Bilophila; Bilophila sp900553145 | |||||||||||
| CAZyme ID | MGYG000001631_01090 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Polyketide synthase PksJ | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 8744; End: 15031 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd05930 | A_NRPS | 0.0 | 1246 | 1753 | 1 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| PRK12467 | PRK12467 | 0.0 | 39 | 1861 | 535 | 2188 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 0.0 | 9 | 1862 | 7 | 1728 | peptide synthase; Validated |
| PRK12467 | PRK12467 | 1.14e-173 | 754 | 1840 | 45 | 1097 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 1.77e-167 | 17 | 1867 | 2009 | 3648 | peptide synthase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAY30132.1 | 1.97e-145 | 667 | 1970 | 2141 | 3422 |
| BAY90071.1 | 6.11e-145 | 571 | 1970 | 2113 | 3411 |
| BAZ00088.1 | 1.26e-140 | 593 | 1970 | 2147 | 3420 |
| BAZ75991.1 | 1.26e-140 | 593 | 1970 | 2147 | 3420 |
| QND46664.1 | 1.34e-122 | 176 | 1978 | 76 | 1736 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7LY7_A | 5.28e-139 | 777 | 1843 | 27 | 1018 | ChainA, BmdB, Bacillamide NRPS [Thermoactinomyces vulgaris] |
| 7LY4_E | 5.41e-139 | 777 | 1843 | 27 | 1018 | ChainE, BmdB, bacillamide NRPS [Thermoactinomyces vulgaris] |
| 2VSQ_A | 7.67e-131 | 782 | 1990 | 31 | 1175 | Structureof surfactin A synthetase C (SrfA-C), a nonribosomal peptide synthetase termination module [Bacillus subtilis] |
| 4ZXH_A | 5.36e-116 | 830 | 1967 | 89 | 1168 | ChainA, ABBFA_003403 [Acinetobacter baumannii AB307-0294],4ZXI_A Chain A, Tyrocidine synthetase 3 [Acinetobacter baumannii AB307-0294] |
| 5ES5_A | 2.75e-114 | 1216 | 1836 | 188 | 760 | Crystalstructure of the initiation module of LgrA in the 'open' and 'closed ' adenylation states [Brevibacillus parabrevis],5ES5_B Crystal structure of the initiation module of LgrA in the 'open' and 'closed ' adenylation states [Brevibacillus parabrevis],5ES8_A Crystal structure of the initiation module of LgrA in the thiolation state [Brevibacillus parabrevis],5ES8_B Crystal structure of the initiation module of LgrA in the thiolation state [Brevibacillus parabrevis],5ES9_A Crystal structure of the LgrA initiation module in the formylation state [Brevibacillus parabrevis],5ES9_B Crystal structure of the LgrA initiation module in the formylation state [Brevibacillus parabrevis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P40806 | 3.50e-196 | 5 | 1850 | 17 | 1735 | Polyketide synthase PksJ OS=Bacillus subtilis (strain 168) OX=224308 GN=pksJ PE=1 SV=3 |
| P45745 | 5.38e-152 | 43 | 1966 | 485 | 2231 | Dimodular nonribosomal peptide synthase OS=Bacillus subtilis (strain 168) OX=224308 GN=dhbF PE=1 SV=4 |
| O30409 | 1.57e-150 | 293 | 1964 | 4864 | 6343 | Tyrocidine synthase 3 OS=Brevibacillus parabrevis OX=54914 GN=tycC PE=1 SV=1 |
| Q70LM5 | 3.79e-148 | 8 | 1963 | 465 | 2242 | Linear gramicidin synthase subunit C OS=Brevibacillus parabrevis OX=54914 GN=lgrC PE=3 SV=1 |
| Q70LM6 | 1.21e-144 | 8 | 1854 | 456 | 2113 | Linear gramicidin synthase subunit B OS=Brevibacillus parabrevis OX=54914 GN=lgrB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000050 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |